Bioconversion of potato solid waste into antifungals and biopigments using Streptomyces spp.

Potato waste was processed and used as a sole substrate for simultaneously producing antifungals and biopigments using Streptomyces spp. Out of three different Streptomyces isolates, strain SO6 stood out due to its ability to produce antifungals against economically important fungal phytopathogens and intracellular biopigments using potato waste powders without additional nutrients. This strain also showed the potential to secrete a broad range of enzymes for fermentation of eight sugars that could be involved in potato waste bioconversion.

Acetylcholinesterase inhibitory activity from growing in Chile: enzymatic and molecular docking studies.

Alkaloid profiles from plants collected in Chile were examined by GC-MS to assess their inhibitory activity on acetylcholinesterase (AChE) using and methodologies. The alkaloid extract was roughly separated by column chromatography on silica gel. AChE inhibitory activities from extracts and purified alkaloids were tested by the Ellman method and a molecular docking study was performed to assess the interaction between AChE and purified alkaloids.