Cytotoxic and DNA-binding Capacity of Titanocene Functionalized Mesoporous Nanoparticles in Breast Cancer Cell Lines MCF-7 and MDA-MB-231.

Aims: The fight against cancer is an active research topic that combines several disciplines to find suitable agents to treat various tumours.

Background: Following cisplatin, organometallic compounds, including titanocene derivatives, have been tested as antitumoral agents. However, key issues still need to be addressed in metallodrug chemotherapy relating to solubility, stability, and dosage.