Pancreatosteatosis in patients with adrenal incidentaloma: A risk factor for impaired glucose metabolism.

Aims: Patients with adrenal incidentaloma (AI) are at increased risk of impaired glucose metabolism, which is known to be associated with pancreatosteatosis (PS). We aimed to investigate the risk of developing dysglycemia for patients with non-functioning AI (NFAI) versus those without, and whether the presence of PS predicts future dysglycemia in patients with NFAI.

Method: In 80 patients with NFAI and 127 controls matched for age, sex, and body mass index, changes in fasting plasma glucose (FPG) and hemoglobin A1c(HbA1c) were evaluated at 2 years.

A New Filter Approach Based on Effective Ranges for Classification of Gene Expression Data.

Over the years, many studies have been carried out to reduce and eliminate the effects of diseases on human health. Gene expression data sets play a critical role in diagnosing and treating diseases. These data sets consist of thousands of genes and a small number of sample sizes.

Momordica charantia Enhances Tendon Healing in Rats: An Experimental Study.

Momordica charantia (MC) is a traditional plant widely used since ancient times for wound healing. This study evaluated its potential effects on tendon healing. Adult male Wistar albino rats (n = 32, 8 rats in each group) were anesthetized, and their Achilles tendons were prepared for surgical procedures.

The effects of myricitrin and chebulinic acid on the rat hippocampus exposed to gamma radiation: A stereological, histochemical and biochemical study.

Aim: Gamma radiation, a form of ionizing radiation, is used in many different areas, especially in the health field and in the treatment of cancer. However, gamma radiation used for therapeutic purposes also has numerous harmful effects on human health. This study was planned to investigate the impacts of exposure to gamma radiation on the hippocampal area and the preventive effects of myricitrin and chebulinic acid against that damage.

WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium.

The correct intraflagellar transport (IFT) assembly at the ciliary base and the IFT turnaround at the ciliary tip are key for the IFT to perform its function, but we still have poor understanding about how these processes are regulated. Here, we identify WDR31 as a new ciliary protein, and analysis from zebrafish and reveals the role of in regulating the cilia morphology. We find that loss of WDR-31 together with RP-2 and ELMD-1 (the sole ortholog ELMOD1-3) results in ciliary accumulations of IFT Complex B components and KIF17 kinesin, with fewer IFT/BBSome particles traveling along cilia in both anterograde and retrograde directions, suggesting that the IFT/BBSome entry into the cilia and exit from the cilia are impacted.

Applications of various stereological tools for estimation of biological tissues.

To provide concise and brief important stereological application methods and techniques for estimating biological tissues. Stereology studies the quantity of biological tissue using little practice and the low price of counting and preparing tissue slices to obtain direct and accurate results. Since their establishment, the stereological techniques underwent much improvement, thus allowing more precise analysis of target structures using various approaches.

Protective effect of indole-3-carbinol on testis of a high fat diet induced obesity.

We investigated the effects of obesity caused by a high fat diet (HFD) on rat testes and evaluated the possible protective effects of indole-3-carbinol (IND). We used 24 8-10-week-old 200 g male rats randomly assigned to 4 groups: non-obese control (NC), obese control (OC), non-obese IND group (NI), obese + IND group (OI). Testis samples were examined using stereological, immunohistochemical, biochemical and histological methods.

Evaluation of the effectiveness of a mobile application in the management of dental anxiety: A randomised controlled trial.

Background: The software, which was developed according to the principle of perceived control, can be installed on tablets and smartphones and used by patients to help them control their anxiety.

Objective: The aim of this study was to evaluate the effectiveness of a specially designed mobile application developed to provide patients with a sense of anxiety control during the various stages of endodontic treatment. The patients' anxiety was assessed by measuring their salivary cortisol levels.

Potential Effects of Stem Cells Derived from the Peripheral Nerve and Adipose Tissue after the Nerve Crush Injury in Control and Obese Rats.

Aim of this study is to investigate effects of stem cells derived from the peripheral nerve and adipose tissues following the nerve crush injury in control and obese rats. For this aim, 41 Wistar Albino female rats were separated into eight equal groups; non-obese control (NOC) obese control (OC), non-obese injury (NOH), obese injury (OH), non-obese adipose (NOY), obese adipose (OY), non-obese nerve (NOPS), obese nerve (OPS). At the end of 8 weeks, all experimental animals without control groups were subjected to nerve crush procedure and sciatic nerve or fat stem cell homogenates were injected on the treatment group rats, and then, recovery process has been observed and histopathological, stereological, electrophysiological analyses and bioinformatic evaluation were made on removed sciatic nerves.

Stereological and Histological Assessment of the Umbilical Cord in New-Born Rat.

Background: Umbilical cord plays a crucial role in the continuation of pregnancy by transferring nutrition and oxygen across the placenta to the fetus. We aimed to investigate the morphometrical and histological features of the umbilical cords in new-born rats.

Materials And Methods: The adult male and female rats were chosen for matting purpose in the present study.

Does the horizontal condylar angle have a relationship to temporomandibular joint osteoarthritis and condylar position? A cone-beam computed tomography study.

Background: The aim of the study was to evaluate the relationship between the horizontal condylar angle (HCA), temporomandibular joint osteoarthritis (TMJ OA), and condylar position on cone-beam computed tomography (CBCT) images.

Materials And Methods: Based on TMJ OA, joints were classified as affected and the unaffected. According to the OA condition of their joints, three groups of patients were formed: control group (n = 159, 41.

Dental Anomalies in Consanguineous Marriage: A Clinical-Radiological Study.

Objective: This study aimed to evaluate nonsyndromic developmental dental anomalies (DDAs) in individuals born from consanguineous and nonconsanguineous marriages and the possible effects of these marriages on self-reported systemic diseases.

Methods: The study comprised a total of 880 patients aged 16 years or older who applied to our clinic for various dental problems. Based on detailed anamnesis, the patients were divided into 2 groups: individuals born from consanguineous (study group, n = 445) and nonconsanguineous (control group, n = 435) marriages.

Idiopathic coronal resorption in impacted permanent teeth and its relationship with age: radiologic study.

Purpose: The purpose of this study was to evaluate the relationship between idiopathic coronal resorption and age in adult patients.

Materials And Methods: 3405 digital panoramic radiographs present in the archive of the radiology department belonging to 1584 males and 1821 females aged 25 and over were assessed by two oral and maxillofacial radiologists. The patients' age, gender, number of impacted teeth, number and position of teeth with idiopathic coronal resorption and the extent of coronal resorption were recorded on standard forms.

Hippocampal neural cell loss in high-fat diet-induced obese rats-exploring the protein networks, ultrastructure, biochemical and bioinformatical markers.

Objective: Obesity, which has become one of the main health problems, results from irregular and unhealthy nutrition. In particular, an increase in the intake of high-fat foods leads to obesity and associated disorders. It is noteworthy to specify that obese individuals have memory problems.

Effects of tacrolimus on c-fos in hippocampus and memory performances in streptozotocin model of Alzheimer’s disease of rats.

Background/aim: Calcineurin, an inhibitor of calcium dependent phosphatase is highly presented in a brain of an Alzheimer’s disease. Aging brain gets more sensitive to hyperactivation of calcineurin, and this event causes tau neurofibrillary plaque accumulation, which is one of the outcomes of this disease. The regions of hippocampus are much effected from the results of this process.

Turkish adaptation and implementation of the modified infection control questionnaire in intraoral digital imaging.

Purpose: There are very few studies evaluating the knowledge of dentists about infection precautions in oral radiology. The aim of this study was to assess the psychometric properties of the Turkish version of the modified form of a developed questionnaire and to apply this questionnaire to Turkish dentists.

Materials And Methods: The questionnaire was applied to a sample of 250 dentists for the scale development [200 for confirmatory factor analysis (CFA) and 50 for control] and 173 dentists for the implementation of the scale.

Is vagal stimulation or inhibition benefit on the regulation of the stomach brain axis in obesity?

Possible effects of the vagus inhibition and stimulation on the hypothalamic nuclei, myenteric plexes and the vagus nerve were investigated. The female rats divided to the inhibition (INH), stimulation (STI) and, sham (SHAM) groups were fed with high fat diet (including 40% of energy from animal fat). After nine weeks, the rats were allowed to recover for 4 weeks in INH group.

The morphometrical and immunohistochemical investigation of the effect of topiramate on liver and the role of neuropeptide Y receptor in an obese female rat.

Objective: We aimed to investigate the possible effect of topiramate (TOP, 0.02 mg/kg/day) on the livers in a high-fat diet (HFD)-induced obesity rat model. The other objective was to evaluate the relationship between TOP administration and NPY level using anti-NPY1R antibody.

Effect of Luteolin on Biochemical, Immunohistochemical, and Morphometrical Changes in Rat Spinal Cord following Exposure to a 900 MHz Electromagnetic Field.

Objective: This study aimed to investigate the effect of exposure to a 900 MHz electromagnetic field (EMF) on the cervical spinal cord (CSC) of rats and the possible protective effect of luteolin (LUT) against CSC tissue damage.

Methods: Quantitative data were obtained stereological, biochemical, immunohistochemical, and histopathological techniques. We investigated morphometric value, superoxide dismutase (SOD) level, and the expression of high-mobility group box 1 protein molecules, as well as histological changes.

Evaluation of the frequency of third molar agenesis according to different age groups.

Purpose: Third molars (M3s) are the most common congenitally missing teeth. The aim of this study was to compare the frequency of M3 agenesis in two different age groups.

Methods: This study examined the panoramic radiographic images of 1036 patients.

Neuroprotective efficacy of luteolin on a 900-MHz electromagnetic field-induced cerebellar alteration in adult male rat.

The adverse health consequences of exposure to electromagnetic field emitted from cell phone has recently raised public concerns worldwide. Also, the Global System for Mobile Communications (GSM) standard that operates in 900 MHz frequency is the most popular. Therefore, we aimed to investigate the adverse effect of exposure to 900 MHz EMF (1 h/day) on the cerebella of 12-week-old rats.

Knowledge, behavior, and awareness of neonatologists and anesthesiologists about oral complications of intubation and protection methods.

Objectives: This study aimed to assess awareness of anesthesiologists and neonatologists about oral complications occurring during and after the orotracheal intubation (OTI) in premature infants and their knowledge and behavior regarding protection methods from these complications in clinical practice.

Methods: This study included 94 neonatologists and 137 anesthesiologist. The final version of the questionnaire included 15 items in three main parts: (i) personal information; (ii) awareness about oral complications occurring during and after the OTI in premature infants; (iii) knowledge and behavior regarding protection methods from these complications in clinical practice.

Mechanical Allodynia in Healthy Teeth Adjacent and Contralateral to Endodontically Diseased Teeth: A Clinical Study.

Introduction: The aims of this study were to examine whether teeth adjacent and contralateral to endodontically diseased teeth showed co-occurring mechanical allodynia and to determine whether demographic and clinical variables were involved in such associations.

Methods: Patients with irreversibly inflamed or necrotic permanent first molars or second premolars were examined. From the 348 eligible patients (160 men and 188 women; mean age ± standard deviation = 30.