Potential Crown Discoloration Induced by the Combination of Various Intracanal Medicaments and Scaffolds Applied in Regenerative Endodontic Therapy.

Background: Regenerative endodontics involves the use of various root canal medicaments and scaffolds, which may cause crown discoloration.

Aim: This study aimed to investigate the combined crown discoloration of scaffolds [platelet-rich fibrin (PRF) and blood clot] applied after administration of different medicaments [modified triple antibiotic paste including doxycycline (mTAPd), modified double antibiotic paste (mDAP), calcium hydroxide (CH), and propolis].

Methods: In total, 100 human mandibular premolar teeth were selected and prepared.

Development of super nanoantimicrobials combining AgCl, tetracycline and benzalkonium chloride.

In this work, we demonstrate that a simple argentometric titration is a scalable, fast, green and robust approach for producing AgCl/antibiotic hybrid antimicrobial materials. We titrated AgNO into tetracycline hydrochloride (TCH) aqueous solution, thus forming AgCl/TCH in a one-step procedure. Furthermore, we investigated the one-pot synthesis of triply synergistic super-nanoantimicrobials, combining an inorganic source of Ag ions (AgCl), a disinfecting agent (benzyl-dimethyl-hexadecyl-ammonium chloride, BAC) and a molecular antibiotic (tetracycline hydrochloride, TCH).

Investigation on Gold Dissolution Performance and Mechanism in Imidazolium Cyanate Ionic Liquids.

To explore green gold leaching reagents, a series of imidazolium cyanate ionic liquids (ILs), 1-ethyl-3-methyl-imidazolium cyanate ([CMIM][OCN]), 1-propyl-3-methyl-imidazolium cyanate ([CMIM][OCN]) and 1-butyl-3-methyl-imidazolcyanate ([CMIM][OCN]) were synthesized and characterized by Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR) and thermogravimetric (TG) analysis. In this research, the imidazolium cyanates were utilized as a solute, which not only decreased the usage of ILs but also increased their gold dissolution capability. The gold dissolution performances of three imidazolium cyanates were characterized by dynamic leaching test and Scanning Electron Microscopy (SEM).

Molecular dynamics simulations of the solubility and conformation change of chitosan grafted polyacrylamide: Impact of grafting rate.

Graft modification is an effective approach to improve the water solubility and molecular weight of chitosan. This work investigated the effect of grafting rate on water solubility of chitosan-grafted polyacrylamide (Chi-g-PAM) using molecular dynamics simulations. The intramolecular and intermolecular interaction between Chi-g-PAM with the grafting rate of 100%-250% and water together with the conformation change were analyzed by radial distribution function (RDF), radius of gyration, solvation free energy (ΔG), mean square displacement, diffusion coefficient and shear viscosity.

Using staining as reference for spectral imaging: Its application for the development of an analytical method to predict the presence of bacterial biofilms.

At present, although spectral imaging is known to have a great potential to provide a massive amount of valuable information, the lack of reference methods remains as one of the bottlenecks to access the full capacity of this technique. This work aims to present a staining-based reference method with digital image treatment for spectral imaging, in order to propose a fast, efficient, contactless and non-invasive analytical method to predict the presence of biofilms. Spectral images of Pseudomonasaeruginosa biofilms formed on high density polyethylene coupons were acquired in visible and near infrared (vis-NIR) range between 400 and 1000 nm.

A simple method for assessing rotational flexibility in adolescent idiopathic scoliosis: modified Adam's forward bending test.

Purpose: This study aimed to evaluate the diagnostic aptitude of a modified Adams forward bending test (MAFBT), which addresses the coupling phenomenon of axial rotation with reference to the side-bending movement. Also, this evaluation was facilitated by the introduction of our rotational flexibility index (RFI).

Methods: Thirty-two female and eight male AIS patients were included in this study from a single institution.

How the stiletto heeled shoes which are popularly preferred by many women affect balance and functional skills?

We aimed at investigating the effects of using stiletto style shoes with different heel heights on balance and climbing up the stairs. Assessments were conducted in three conditions (barefoot, 4 cm, 10 cm heels) on 40 women who are familiar with stiletto heels. In conclusion, when stilletto heeled shoes were worn, both balance and climbing up the stairs got worsen.

Determination of Rational Drug Use Behaviors of Adult Individuals - A Cross-Sectional Study from Turkey.

Purpose: The aim of this study was to determine rational drug usage behaviour of adults.

Material/methods: The study was descriptive and cross-sectional. The study was conducted between January-March 2014 in Mustafa Kemal Paşa Cevizli Family Health Center in the province of Bursa, Turkey.

The effect of equine-derived bone protein extract (Colloss-E) in the treatment of cavitary bone defects: an experimental study.

Objective: Bone protein extract (BPE) usually requires a carrier or a scaffold for implantation. We aimed to compare the effect of equine-derived BPE, an osteoinductive agent composed of a high amount of type-I collagen and other bone proteins (Colloss-E), with that of human demineralized bone matrix (DBM) for treating cavitary bone defects not requiring scaffold use.

Methods: Rabbit distal femoral condyle was used as a stable cavitary bone defect model.

Biomechanical comparison of effects of the Dynesys and Coflex dynamic stabilization systems on range of motion and loading characteristics in the lumbar spine: a finite element study.

Background: The primary purpose of dynamic stabilization is to preserve the normal range of motion (ROM) by restricting abnormal movement in the spine. Our aim was to analyze the effects of two different dynamic stabilization systems using finite element modeling (FEM).

Methods: Coflex and Dynesys dynamic devices were modeled and implanted at the L4-L5 segment using virtual FEM.

Ziprasidone induced tardive cervical dystonia.

Fifty years old female patient used 80 mg/day ziprasidone for 4 months after diagnosed as atypical depression. After 4 months of ziprasidone treatment, involuntary movements appeared in her neck region. Ziprasidone was stopped in by tapering 20 mg/day, but the involuntary movements continued and even exacerbated.

Effect of strontium ranelate on hydrogen peroxide-induced apoptosis of CRL-11372 cells.

In vitro and in vivo studies have proven strontium to be an osteoinductive trace element. The effect of strontium ranelate (SR) on H(2)O(2)-induced apoptosis of CRL-11372 cells and optimization of its anti-apoptotic dose were the aims of this study. After 1 h of pretreatment with SR 1 microM, 50 microM, 100 microM, 500 microM, and 1,000 microM concentrations, CRL-11372 osteoblasts were exposed to 100 microM H(2)O(2) for periods of 6-12 h.

A novel biodegradable PCL film for tendon reconstruction: Achilles tendon defect model in rats.

This study aims to investigate applicability of poly(epsilon-caprolactone) (PCL) biodegradable films for repair of gaps in Achilles tendons in a rat model, also comparing surgical repair versus no repair approaches. PCL was synthesized with tailor-made properties, then, PCL films were prepared by solvent casting. Seventy-five outbred Sprague-Dawley rats were randomly allocated into five groups: (i) sham operated (skin incision only); (ii) no repair (complete division of the Achilles tendon and plantaris tendon without repair); (iii) Achilles repair (with a modified Kessler type suture); and (iv) plasty of Achilles tendon defects with the biodegradable PCL films, and (v) animals subjected to 1 cm mid-substance defect with no repair.

Alcohol neurolysis for persistent pain caused by superior cluneal nerves injury after iliac crest bone graft harvesting in orthopedic surgery: report of four cases and review of the literature.

Study Design: Harvesting of autologous bone graft from the posterior iliac crest for lumbar spinal fusions is a frequently performed procedure in orthopedic surgery. The most common complication associated with this procedure is an alteration in sensation over the donor site manifested as chronic pain, hyperesthesia, dysesthesia, or diminished sensitivity resulting from superior cluneal nerve (SCN) injury.

Objective: To predict the effectiveness of alcohol neurolysis in the treatment of persistent pain caused by the entrapment of superior cluneal nerves.

Relevance of mangled extremity severity score to compartment syndromes.

This study investigated the relevance of a mangled extremity severity score (MESS) to the evaluation of intracompartmental pressure in injured patients. We measured intracompartmental pressures with a modification of the Whitesides method and compared these values with MESS in 27 patients after trauma. For 5 of them fasciotomy was necessary to relieve high intracompartmental pressures.