Assessment of Non-Vitamin K Antagonist Oral Anticoagulant Dosing Patterns in Turkish Patients with Non-Valvular Atrial Fibrillation: A Multicenter, Cross-Sectional Study with Insights from the ASPECT-NOAC Study.

Objective: We aimed to assess the real-world label adherence of non-vitamin K antagonist oral anticoagulant (NOAC) dosing patterns, including apixaban, edoxaban, and rivaroxaban, in Turkish patients with atrial fibrillation.

Methods: This was an observational, prospective, cross-sectional, multicenter study. Patients with atrial fibrillation (AF) who were prescribed NOACs within the last 4 months were recruited from 34 cardiology clinics in Türkiye.

Genital Attacks in Hereditary Angioedema and Their Effects on Sexual Life.

: Hereditary angioedema (HAE) is characterized by unpredictable skin and mucosal angioedema attacks. We aimed to find the frequency of sexual-activity-triggered attacks (STAs) and understand how the sexual life of HAE with C1-inhibitor deficiency (HAE-C1INH) patients is affected. : Adult HAE-C1INH patients were included in this cross-sectional study, which started in March 2020.

Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-2: Specific Entities, Risk Stratification and Challenges After Recovery).

Takotsubo syndrome (TTS) still remains as an enigmatic phenomenon. In particular, long-term challenges (including clinical recurrence and persistent symptoms) and specific entities in the setting of TTS have been the evolving areas of interest. On the other hand, a significant gap still exists regarding the proper risk-stratification of this phenomenon in the short and long terms.

Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-1: Diagnostic and Therapeutic Challenges).

In the recent years, there has been a burgeoning interest in Takotsubo syndrome (TTS), which is renowned as a specific form of reversible myocardial dysfunction. Despite the extensive literature available on TTS, clinicians still face several practical challenges associated with the diagnosis and management of this phenomenon. This potentially results in the underdiagnosis and improper management of TTS in clinical practice.

People are skeptical of headlines labeled as AI-generated, even if true or human-made, because they assume full AI automation.

The rise of generative AI tools has sparked debates about the labeling of AI-generated content. Yet, the impact of such labels remains uncertain. In two preregistered online experiments among US and UK participants ( = 4,976), we show that while participants did not equate "AI-generated" with "False," labeling headlines as AI-generated lowered their perceived accuracy and participants' willingness to share them, regardless of whether the headlines were true or false, and created by humans or AI.

Media literacy tips promoting reliable news improve discernment and enhance trust in traditional media.

Media literacy tips typically encourage people to be skeptical of the news despite the small prevalence of false news in Western democracies. Would such tips be effective if they promoted trust in true news instead? A pre-registered experiment (N = 3919, US) showed that Skepticism-enhancing tips, Trust-inducing tips, and a mix of both tips, increased participants' sharing and accuracy discernment. The Trust-inducing tips boosted true news sharing and acceptance, the Skepticism-enhancing tips hindered false news sharing and acceptance, while the Mixed tips did both.

Hypertension and Occupational Health: A General Overview and Expert Consensus Suggestions.

Hypertension is a common public health issue, and its incidene increases parallel to age. It is inevitable that certain occupational conditions may pose risks for high blood pressure or cause difficulties in managing blood pressure. Working under specific circumstances may compromise the safety of individuals with hypertension and potentially others.

Psychosocial Evaluation of Adults with Primary Immunodeficiency.

Purpose: Primary immunodeficiency disorder (PID) is a heterogeneous group of diseases characterized by immune dysregulation and increased susceptibility to infections, with various cognitive, emotional, behavioral, and social effects on patients. This study aimed to evaluate loneliness, social adaptation, anxiety, and depression and to identify associated factors in adults with immunodeficiency.

Methods: A cross-sectional study in Turkey (Feb-Aug 2022) obtained sociodemographic data from patient records.

Multivariate analysis of clinical and radiological risk factors for revision endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyps: can phenotype predict recurrence?

Objective: This study aimed to analyse clinical and radiological features (phenotypes) to predict revision risk after functional endoscopic sinus surgery in patients with chronic rhinosinusitis with nasal polyps.

Method: Phenotype characteristics of the patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery were analysed retrospectively.

Results: The rates of asthma, aspirin sensitivity, smoking and a positive prick test result were significantly higher in revision functional endoscopic sinus surgery cases ( < 0.

Relationship between adiponectin and copeptin levels with long-term cardiovascular mortality in ST-segment elevation myocardial infarction after percutaneous coronary intervention.

Objective: The aim of this study was to determine adiponectin and copeptin levels that might be prognostic for cardiovascular mortality (CvsM) in ST-segment elevation myocardial infarction (STEMI) patients who had percutaneous coronary intervention (PCI).

Methods: Patients who underwent PCI between November 2010 and April 2011 were enrolled and followed for more than eight years. The baseline, demographic and angiographic findings, in-hospital follow up, laboratory results including adiponectin and copeptin levels, and echocardiographic data of the patients were evaluated.

Real-World Data on the Incidence of Stroke, Myocardial Infarction, and Mortality Among Nonvalvular Atrial Fibrillation Patients in Türkiye: New Oral Anticoagulants-TURKey Study.

Background: Atrial fibrillation (AF) is strongly associated with an increased risk of ischemic events. Anticoagulation focuses on reducing the risk of embolism. Guideline recommended CHA2DS2-VASc scoring system is most widely used; however, different scoring systems do exist.

A Fatal Disaster: Accompanying Aortic Dissection Obscured by Acute Coronary Syndrome.

The present study investigated the characteristics of rare but often fatal cases of acute coronary syndrome and aortic dissection and the factors affecting mortality. HEART score, aortic dissection detection risk score, and Global Registry of Acute Coronary Event (GRACE) Score were calculated by evaluating biochemical tests and symptoms/signs of the 20 patients who were admitted to our clinic with a preliminary diagnosis of acute myocardial infarction and subsequently diagnosed with aortic dissection. The assumption of normal distribution was checked with the Shapiro-Wilk test, and independent group comparisons were made with the test or the Mann-Whitney U test.

Smartphone use and well-being in Pakistan: Comparing the effect of self-reported and actual smartphone use.

Objective: Past work has shown that smartphone use has negative effects on well-being. Yet, most evidence relies on self-reported measures of smartphone use and comes from Western democracies. We examined the relationship between both self-reported and actual smartphone use and well-being in Pakistan, a country that is under-researched in the Global South.

A Narrative Review of the Association of Obstructive Sleep Apnea with Hypertension: How to Treat Both When They Coexist?

Hypertension (HT) is a worldwide public health issue and an essential risk factor for cardiovascular and cerebrovascular diseases. Obstructive sleep apnea (OSA) is a condition characterized by recurrent episodes of apnea and hypopnea as a consequence of partial or complete obstruction of the upper airways due to anatomic and/or functional disturbances. There is mounting evidence of a relationship between OSA and HT.

Integrating the Left Atrium Diameter to Improve the Predictive Ability of the Age, Creatinine, and Ejection Fraction Score for Atrial Fibrillation Recurrence After Cryoballoon Ablation.

Background: Several clinical trials have assessed predictors for atrial fibrillation recurrence following cryoballoon catheter ablation. With these predictors, a practical and new scoring system can be developed to evaluate atrial fibrillation recurrence. The present study aimed to analyze the predictive value of the age, creatinine, and ejection fraction-left atrium score for potential recurrence of atrial fibrillation following cryoballoon catheter ablation in patients with symptomatic paroxysmal or persistent atrial fibrillation.

Obstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?

Obstructive sleep apnea is common in adults with cardiovascular disease. Accumulating evidence suggests an association between obstructive sleep apnea and cardiovascular disease independent of the traditionally recognized cardiovascular disease risk factors. Observational studies indicate that obstructive sleep apnea is a risk factor for development of cardiovascular disease and that alleviation of obstructive events with positive airway pressure may improve cardiovascular disease outcomes.

Conspiracy believers claim to be free thinkers but (Under)Use advice like everyone else.

Conspiracy believers often claim to be critical thinkers their 'own research' instead of relying on others' testimony. In two preregistered behavioural studies conducted in the United Kingdom and Pakistan (N  = 864, N  = 5408), we test whether conspiracy believers have a general tendency to discount social information (in favour of their own opinions and intuitions). We found that conspiracy mentality is not associated with social information use in text-based (Study 1) and image-based (Study 2) advice-taking tasks.

Happy thoughts: The role of communion in accepting and sharing (mis)beliefs.

The negativity bias favours the cultural diffusion of negative beliefs, yet many common (mis)beliefs-naturopathy works, there's a heaven-are positive. Why? People might share 'happy thoughts'-beliefs that might make others happy-to display their kindness. Five experiments conducted among Japanese and English-speaking participants (N = 2412) show that: (i) people higher on communion are more likely to believe and share happier beliefs, by contrast with people higher in competence and dominance; (ii) when they want to appear nice and kind, rather than competent and dominant, people avoid sharing sad beliefs, and instead prefer sharing happy beliefs; (iii) sharing happier beliefs instead of sad beliefs leads to being perceived as nicer and kinder; and (iv) sharing happy beliefs instead of sad beliefs fleads to being perceived as less dominant.