Sun protection behaviour and skin cancer literacy among outdoor runners.

Outdoor runners have an increased risk of melanoma and non-melanoma skin cancer. The purpose of this study was to assess skin cancer literacy and sun exposure and protection behaviour among outdoor runners during training. A cross-sectional survey-based study was conducted.

Ophthalmic adverse drug reactions to systemic drugs: a systematic review.

Purpose: To perform a comprehensive and systematic review regarding ophthalmic adverse drug reactions (ADRs) to systemic drugs to: (i) systematically summarize existing evidence, (ii) identify areas, ophthalmic ADRs or drugs that lacked systematization or assessment (namely drugs with original studies characterizing specific ophthalmic ADRs but without causality assessment nor without meta-analysis).

Methods: Systematic review of several electronic databases (last search 1/7/2012): Medline, SCOPUS, ISI web of knowledge, ISI Conference Proceedings, International Pharmaceutical Abstracts and Google scholar. Search query included: eye, ocular, ophthalmic, ophthalmology, adverse and reaction.

A survey of spontaneous reporting of adverse drug reactions in 10 years of activity in a pharmacovigilance centre in Portugal.

Objective: Reporting of adverse drug reactions (ADRs) may differ between countries.

Methods: In a retrospective descriptive study we analysed the potential causative drugs and clinical situations related to spontaneously reported ADRs over 10 years to a regional pharmacovigilance centre in Portugal.

Key Findings: We collected 3165 cases (36% of all national reports) of ADRs reported by doctors (54%), pharmacists (31%), and nurses (15%), 56% of which were classified as serious, 22% as unexpected and 13% as both serious and unexpected.

Detection of adverse drug reactions using hospital databases-a nationwide study in Portugal.

Purpose: This study aimed to detect and characterize adverse drug reactions (ADRs) that occurred during hospitalization (ADRIn ) and ADRs associated with admission (ADRAd ) in Portugal from 2000 to 2009. We also intended to compare the results of this methodology with spontaneous reporting.

Methods: We conducted a nationwide study using a hospital administrative database that included all acute care public hospitalizations in Portugal, from 2000 to 2009.

Methodologies for the detection of adverse drug reactions: comparison of hospital databases, chart review and spontaneous reporting.

Purpose: To evaluate a methodology for adverse drug reactions (ADRs) detection through hospital databases.

Methods: A retrospective analysis was conducted to identify ADRs using diagnostic codes from databases, later validated by chart review. An independent chart review was performed for comparison, as well as assessment of spontaneous reports.

Frequency of adverse drug reactions in hospitalized patients: a systematic review and meta-analysis.

Purposes: To perform a comprehensive systematic review of prospective studies about frequency of adverse drug reactions (ADRs) occurring during hospitalization (ADR(In) ), including a thorough study quality assessment, meta-analysis and heterogeneity evaluation.

Methods: Systematic review of several databases: Pubmed, EMBASE, CINAHL, Cochrane, ISI, International Pharmaceutical Abstracts, Scirus, NHS economic, and others, as well as manual search. Inclusion criteria were: prospective studies (assessing all patients before discharge, by a specialized team, at least once a week); with data about ADRs occurring during hospitalization, using WHO's or similar definition of ADR.

[Analysis of maternal and child health indicators: the parallel between Portugal and Brazil].

Purpose: To analyze comparatively the conditions of birth in Portugal and Brazil from 1975 to 2007.

Methods: Indicators of maternal and child health: rates of maternal death and neonatal mortality, cesarean rate and public spending on health were retrospectively collected from electronic databases of health information from the Unified Health System (DATASUS) and the National Institute of Statistics of Portugal (INE), among others. Their values were descriptively analyzed in terms of trends and the temporal sanitary scenarios were presented and discussed, comparing, when possible, the information from the two countries.

Association of anxiety with asthma: subjective and objective outcome measures.

Background: The relationship between anxiety and asthma is currently being intensively studied.

Objective: The authors examined anxiety that influences and is influenced by this complex disease.

Method: The authors conducted a cross-sectional study of adults with asthma at a hospital outpatient department, excluding known psychiatric patients.

Influence of vasopressor agent in septic shock mortality. Results from the Portuguese Community-Acquired Sepsis Study (SACiUCI study).

Objective: Guidelines for the adrenergic support of septic shock are controversial. In patients with community-acquired septic shock, we assessed the impact of the choice of vasopressor support on mortality.

Design: Cohort, multiple center, observational study.