Publications by authors named "Altaf S Almatari"
Article Synopsis
- The study focuses on creating new thiophene analogues as potential anticancer drugs through a multicomponent reaction involving various reagents like ethyl 4-chloroacetoacetate and phenyl isothiocyanate in a special solvent.
- The reaction generated several thiophene derivatives, which were then further modified and characterized through elemental and spectral analysis.
- The cytotoxicity of these new compounds was tested on HepG2, A2780, and A2780CP cell lines, revealing that one derivative showed promising growth inhibition, suggesting potential for future anticancer therapy development.
