Public awareness about arthritic diseases in Saudi Arabia: a systematic review and meta-analysis.

Purpose: Raising public knowledge and perception would have a discernible impact on providing optimal care and reducing the burden of arthritis in the community. This systematic review aimed to identify the public knowledge about the common arthritic conditions in Saudi Arabia.

Methods: We searched MEDLINE, Embase, and CENTRAL for relevant literature.

Utility of Opportunistic Infections, Joints' Involvement and Accuracy of Various Screening Tests to Diagnose Rheumatoid Arthritis Patients.

: Rheumatoid Arthritis (RA) is an auto-immune disease in which the body mistakenly considers some parts of its own system as pathogens and attacks them. Prevalence is approximately 0.75% in India.

Idiopathic Orbital Inflammation Treated With Rituximab Monotherapy.

Idiopathic orbital inflammation is a benign condition that affects the orbit and the extra-orbital structures. It presents as ocular pain, peri-orbital swelling, proptosis, and restricted ocular movements. This condition is diagnosed based on clinical features that are then confirmed by radiological and histopathological findings.

Homozygous Missense Variant in the N-Terminal Region of ANK3 Gene Is Associated with Developmental Delay, Seizures, Speech Abnormality, and Aggressive Behavior.

Introduction: Intellectual disability (ID) is a lifelong disability that affects an individual‧s learning capacity and adaptive behavior. Such individuals depend on their families for day-to-day survival and pose a significant challenge to the healthcare system, especially in developing countries. ID is a heterogeneous condition, and genetic studies are essential to unravel the underlying cellular pathway for brain development and functioning.

New Method Based on the Direct Analysis in Real Time Coupled with Time-of-Flight Mass Spectrometry to Investigate the Thermal Depolymerization of Poly(methyl methacrylate).

In this work, the isothermal decomposition of poly(methyl methacrylate) synthesized in bulk by the radical route of methyl methacrylate in the presence of azobisisobutyronitrile as the initiator was carried out and monitored for the first time with the DART-Tof-MS technique at different temperatures. Nuclear magnetic resonance (NMR) analysis revealed a predominantly atactic microstructure, and size-exclusion chromatography (SEC) analysis indicated a number average molecular weight of 3 × 10 g·mol and a polydispersity index of 2.47 for this polymer.

Improved Wireless Medical Cyber-Physical System (IWMCPS) Based on Machine Learning.

Medical cyber-physical systems (MCPS) represent a platform through which patient health data are acquired by emergent Internet of Things (IoT) sensors, preprocessed locally, and managed through improved machine intelligence algorithms. Wireless medical cyber-physical systems are extensively adopted in the daily practices of medicine, where vast amounts of data are sampled using wireless medical devices and sensors and passed to decision support systems (DSSs). With the development of physical systems incorporating cyber frameworks, cyber threats have far more acute effects, as they are reproduced in the physical environment.

Fatigue and Cognitive Decline Associated With Depressive Symptoms Among Community-Dwelling Adults.

To investigate the prevalence of depressive symptoms in community-dwelling Saudi adults aged ≥50 years and the associated risk factors. Patient Health Questionnaire 9 (PHQ-9) was dichotomized as depressive symptoms when the participants scored ≥10. Risk factors included age, sex, body mass index, education, employment, marital status, number of chronic diseases and medications, fatigue severity scale (FSS), and Montreal Cognitive Assessment (MoCA).

Normative values for hand grip and pinch strength for 6 to 18 year-olds in Saudi Arabia.

Background: Normative values for hand grip and pinch strength among children in Saudi Arabia has not been well established. Therefore, the main aim of this study is to establish normative values for hand grip and pinch strength in children aged 6 to 18 years in Saudi Arabia.

Methods: A cross-sectional study was conducted from different 5 regions in Saudi Arabia.

Ophthalmic Manifestations of Arterial Tortuosity Syndrome: Case Series of Patient and Carriers.

Purpose: The aim of this study was to report the detailed ophthalmic findings in a young patient with genetically confirmed arterial tortuosity syndrome (ATS) and the findings in 8 family members who were carriers.

Methods: Nine members of the same Saudi family were assessed at King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia, for ATS-related ocular changes after homozygosity for the pathogenic variant of SLC2A10 gene was confirmed in 1 member. All family members underwent complete ophthalmic examination, genetic testing, and corneal tomography at presentation and at 6-month follow-up.

The Five Times Sit-to-Stand Test is associated with both history of falls and fear of falling among community adults aged 50 years and older.

Background: Limited evidence has examined the association between balance and mobility measures with risk of fall.

Aim: To determine the prevalence and balance measures associated with falls and fear of falling among community adults aged 50 years and older.

Methods: This cross-sectional study included community-dwelling adults aged ≥ 50 years, living in Saudi Arabia.

Physicians' Knowledge, Practices, and Perceptions of Reporting Communicable Diseases at Primary Health Care Centers in Jeddah, Saudi Arabia: A Cross-Sectional Study.

Background Jeddah has the highest international traffic and is among the most diverse cities in Saudi Arabia. The chance of importing an emerging communicable disease is significant, particularly during the religious seasons. Therefore, timely and accurate reporting of communicable diseases at primary health care centers (PHCCs) is crucial.

Effect of Nitrogen in Combination with Different Levels of Sulfur on Wheat Growth and Yield.

As macronutrients, management of nitrogen (N) and sulfur (S) is prime in importance when wheat is cultivated. Both have a significant impact on the improvement of growth and yield attributes. In addition, S and N also play an imperative role in the enhancement of seed protein contents.

Effect of Resistance Training on Body Composition, Hemodynamic Parameters and Exercise Tolerance among Patients with Coronary Artery Disease: A Systematic Review.

Background: Effectiveness and safety of Resistance Training in treating various Cerebrovascular Disease diagnoses have drawn attention in recent years. Patients suffering with coronary artery disease should be offered individually tailored Resistance Training in their exercise regimen. Resistance Training was developed to help individuals with their functional status, mobility, physical performance, and muscle strength.

Virtual Behavioral Intervention to Promote Healthy Lifestyle Behaviors: A Feasibility RCT during COVID-19 Pandemic.

Background: the COVID-19 pandemic has had a substantial impact on human health, affecting many lifestyle behaviors such as physical activity, sedentary behavior, dietary habits and sleep.

Purpose: to assess the feasibility of six sessions of a virtual behavioral intervention to promote healthy lifestyle practices during a stay-at-home advisory phase of the COVID-19 pandemic.

Methods: A participant-blinded randomized controlled trial was performed through a virtual platform setting.

A cross-sectional study explores the association of physical activity with the severity of peripheral arterial disease from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Engaging in physical activity (PA) has been proved to reduce the risk of developing cardiovascular diseases. In patients with peripheral arterial disease (PAD), diminished PA predicts high overall mortality. However, the extent of the association of participation in PA with PAD severity is unknown.

study revealed the inhibitory activity of selected phytomolecules of against VacA implicated in gastric ulcer.

Gastric ulcer is associated with weakening of the mucous coating of the stomach and damages to the intestinal lining. It is caused by assisted by enzymes including VacA, which necessitates the need for inhibitors of VacA. Bioactive compounds from have been documented to have anti-inflammatory activities.

Health-related quality of life in Welsh adults: psychometric properties of the SF-36v2 and normative data.

Objectives: The use of normative data has become well-accepted and a common strategy to interpret individual's health outcome scores, which can help in making decisions. The objectives of this study were to obtain population normative data for the domains and component summaries of the 36-item SF-36® Health Survey (SF-36), and to evaluate its reliability and construct validity.

Methods: This study was conducted using population-based data from the Welsh Health Survey (WHS; 2011-2015).

An unusual case of gastric angiolipoma presenting with upper gastrointestinal bleeding.

Gastric angiolipomas (GA) are rare benign tumors that can present with gastrointestinal bleeding and anemia. We describe a 73-year-old woman who presented with a 3-day history of fatiguability, epigastric pain and melena. A computed tomography scan revealed a hypodense lesion, measuring 6 × 6 × 5 cm, along the upper part of the stomach.

Metabolic Syndrome and Cardiometabolic Risk Factors in the Mixed Hypercholesterolemic Populations with Respect to Gender, Age, and Obesity in Asir, Saudi Arabia.

This record study aimed to investigate the prevalence of metabolic syndrome (MetS) profiles regarding sex, age, and obesity for the riskier factor of cardiovascular diseases in a general population in Saudi Arabia. Laboratory and anthropometric measurements were performed on non-specific participants with variant ages and BMI in either sex. Serobiochemical changes were measured for metabolic profiles, i.

Smart-Card Technology for the Dental Management of Medically Complex Patients.

Smart-card technology is believed to help healthcare industries in several ways, since it minimizes risks and medical errors, enables accurate patient identification, reduces administrative costs, improves efficiency, and facilitates prompt delivery of care to patients. The present study aims to highlight the adoption of a newly designed dental smart card for medically complex patients. The present smart card is an advance in patient identification, using a quick-response (QR) code to automatically report or receive certain types of responses from patients or physicians once illuminated by signals from QR readers.

Spinal Gunshot Wound With an Air Rifle: A Case Report.

Spinal gunshot injuries are one of the most serious injuries that can cause morbidity and mortality. We report a case of a nine-year-old boy, referred to our emergency department from another hospital, with lower limb weakness after being shot by an air gun in his back. After extensive investigation, it appeared that a foreign body representing the bullet was found in his spinal canal; the patient was taken to the operating room for surgical decompression and removal of foreign bodies.

Methotrexate-Induced Alteration of Renal Aquaporins 1 and 2, Oxidative Stress and Tubular Apoptosis Can Be Attenuated by Omega-3 Fatty Acids Supplementation.

Methotrexate (MTX) is a potent anti-cancer drug, commonly associated with nephrotoxicity via the induction of oxidative stress and apoptosis with alteration of renal water channel proteins, namely aquaporins (AQPs). Omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) have shown cytoprotective effects through their anti-oxidant and antiapoptotic activities. The present study aims for the first time to explore the role of LC-PUFA against MTX-induced nephrotoxicity.

In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer's Disease.

Plants' bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated a flavone 2-(3,4-dimethoxyphenyl)-3,7-dihydroxy-4H-chromen-4-one from and it was evaluated against various targets of the oxidative stress-related neurological disorders.