Oral Health Care for Individuals With Special Needs: Practices and Challenges Among General Practitioners in Saudi Arabia.

Introduction: A vital component of public health that needs a lot of attention is oral health care for people with special needs. The phrase "special needs" describes a wide range of issues pertaining to behavior, development, health, and emotions that require specific medical and educational support. These individuals often present with complex oral health care needs that require specialized knowledge and skills.

Atmospheric pressure spatial atomic layer deposition of p-type CuO thin films from copper(II) acetylacetonate and ozone for UV detection.

Cupric oxide (CuO) is a promising p-type semiconducting oxide used in many critical fields, such as energy conversion and storage, and gas sensors, which is attributed to its unique optoelectrical properties and cost-effectiveness. This work successfully deposited amorphous, pinhole-free, ultrathin CuO films using atmospheric pressure spatial atomic layer deposition (SALD) with copper(II) acetylacetonate and ozone as precursors. The growth rate increased from 0.

Comparison of 4-factor fixed dose versus 4-factor weight-based dose prothrombin complex concentrate for emergent warfarin reversal: a systematic review and meta-analysis.

Objectives: The objective of this systematic review and meta-analysis is to evaluate the efficacy, safety, time to INR reversal, total volume of 4-factor prothrombin complex concentrate (PCC) administered of fixed-dose versus weight-based dosing strategies in patients requiring urgent warfarin reversal, with specific focus on clinical outcomes such as hemostatic efficacy, thromboembolic events, and mortality rates.

Methods: A comprehensive systematic review was conducted using the PubMed, Embase, and Cochrane databases from inception through October 2023. We searched for randomized clinical trials or observational studies that compared efficacy or safety outcomes of fixed-dose vs.

Clinical Characteristics and Outcomes of Deep Vein Thrombosis in Relation to Location: A Retrospective Analysis Study.

Deep vein thrombosis (DVT) is a leading cause of death disability. DVT can be classified based on the location and extent of the clot into isolated distal DVT (iDDVT), isolated proximal DVT (iPDVT), or mixed DVT. The aim of this study is to explore the baseline characteristics and clinical outcomes of patients with different types of DVT.

Evaluating the risk of acute kidney injury and mortality associated with concomitant use of vancomycin with piperacillin/tazobactam or meropenem in critically ill and non-critically ill patients: a systematic review and meta-analysis.

Background: There are conflicting findings regarding the risk of acute kidney injury (AKI) and mortality with vancomycin/piperacillin-tazobactam combination (VPT) and vancomycin/meropenem (VM). The aim of this meta-analysis was to compare the risk of AKI and mortality between VPT and VM.

Methods: Observational studies reporting the incidence of AKI and mortality in patients receiving VPT or VM between January 2017 and September 2024 were retrieved from PubMed, the Cochrane Library, and Web of Science.

The Perils of Methanol Exposure: Insights into Toxicity and Clinical Management.

Methanol is a widely used industrial and household alcohol that poses significant health risks upon exposure. Despite its extensive use, methanol poisoning remains a critical public health concern globally, often resulting from accidental or intentional ingestion and outbreaks linked to contaminated beverages. Methanol toxicity stems from its metabolic conversion to formaldehyde and formic acid, leading to severe metabolic acidosis and multiorgan damage, including profound CNS effects and visual impairments.

Development and Validation of a Green Spectrofluorimetric Method for Nateglinide Quantification: Utilizing AR87 as a Probe With Box-Behnken Optimization and Quantum Mechanical Calculations.

In this study, a sensitive and selective spectrofluorimetric method was developed for the determination of the antidiabetic drug nateglinide based on its reaction with the xanthene dye acid red 87 (AR87). A fluorescence quenching process was observed for the AR87 at 545 nm upon the addition of nateglinide, which was exploited for the quantitative analysis. The reaction mechanism was investigated using quantum mechanical calculations suggesting a transfer between the electron-rich AR87 and the electron-deficient nateglinide.

Corrigendum to "Characterization and potential health benefits of millet flour and banana peel mixtures on rats fed with a high-fat diet" [Heliyon 10(20), October 2024, e39424].

[This corrects the article DOI: 10.1016/j.heliyon.

Debonding Characteristic and Survival Probability of Adhesive Flash-Free Ceramic Orthodontic Brackets Following pH Cycling.

Objectives:  Orthodontic bracket bond failure is an obstacle in clinical orthodontics. This study investigated the influence of pH cycling on the shear bond strength (SBS), adhesive remnant index (ARI), and survival probability of adhesive-precoated flash-free ceramic brackets.

Materials And Methods:  Forty mandibular premolars were randomly divided into two groups ( = 20): C: noncoated orthodontic brackets, and F: flash-free adhesive-precoated orthodontic brackets.

The prevalence of cyberchondria and the impact of skepticism on medical decisions among Imam Mohammed Ibn Saud Islamic University students, Riyadh, Saudi Arabia.

Unlabelled: The internet significantly impacts the occurrence and prevalence of cyberchondria because it provides easy access to a large amount of health data that can describe any medical condition in detail. Cyberchondria develops due to exposure to the vast and easily accessible online health information that causes health worries.

Objectives: To assess the prevalence of cyberchondria among Imam Mohammad Ibn Saud Islamic University (IMSIU) students and determine the impact of patient skepticism on medical decisions.

Awareness and use of tools to identify potentially inappropriate prescribing among physicians and pharmacists in Saudi Arabia: a nationwide cross-sectional study.

Background: Potentially inappropriate prescribing (PIP) contributes significantly to treatment burden, specifically in older people. Detecting PIP and improving prescribing practices are therefore crucial for ensuring patient safety and positive outcomes.

Aim: This study aimed to assess physicians' and pharmacists' awareness and use of tools to identify PIP, as well as their confidence in recommending medication for older people.

EA-CNN: Enhanced attention-CNN with explainable AI for fruit and vegetable classification.

The quality of vegetables and fruits are judged by their visual features. Misclassification of fruits and vegetables lead to a financial loss. To prevent the loss, superstores need to classify fruits and vegetables in terms of size, color and shape.

Evaluation of droperidol use in the emergency department: a retrospective analysis of QTc prolongation and adverse events.

Background: Droperidol is a first-generation antipsychotic medication that has been used for various indications in the emergency department (ED); however, its use has been controversial due to reports of QT prolongation and the risk of torsades de pointes (TdP). The aim of the study is to evaluate the safety of droperidol administration in the ED.

Methods: This was a retrospective study, conducted at an academic level I trauma center.

Primary health care professionals' opinions regarding continuing medical education: A cross sectional study.

Continuing medical education (CME) is the foremost among the learning strategies that enhance knowledge and skills within the medical profession. This study aimed to evaluate primary healthcare professionals' CME in Abha City. A total of 267 primary health care (PHC) professionals.

Accuracy of 3 Intraoral Scanners in Recording Impressions for Full Arch Dental Implant-Supported Prosthesis: An In Vitro Study.

BACKGROUND This study used an edentulous mandibular resin model with 6 parallel osteotomy sites and aimed to compare the accuracy (trueness and precision) of 10 digital impressions using 3 intraoral scanners, the 3Shape TRIOS 5, Medit i700, and Primescan, using Medit Link v3.3.2 software.

Quantitative susceptibility mapping of the fear circuit: Associations with silent symptoms in relapsing-remitting multiple sclerosis.

Multiple sclerosis (MS) is a long-term autoimmune inflammatory disorder that affects the central nervous system leading to neurodegeneration, and can involve a variety of symptoms. These symptoms can include fatigue, anxiety, depression, and cognitive decline, which may be silent. The objective of this study was to explore changes in brain iron deposition in people with relapsing-remitting MS (pw-RRMS) compared to healthy controls (HCs), with a particular focus on regions of fear circuit.

Perirenal Fat CT Radiomics-Based Survival Model for Upper Tract Urothelial Carcinoma: Integrating Texture Features with Clinical Predictors.

Upper tract urothelial carcinoma (UTUC) presents significant challenges in prognostication due to its rarity and complex anatomy. This study introduces a novel approach integrating perirenal fat (PRF) radiomics with clinical factors to enhance prognostic accuracy in UTUC. The study retrospectively analyzed 103 UTUC patients who underwent radical nephroureterectomy.

Eco-friendly synchronous spectrofluorimetry coupled with chemometrics for simultaneous determination of ezetimibe and propranolol in pharmaceutical formulations and spiked plasma samples.

In this study, synchronous fluorescence spectroscopic methods coupled with chemometric techniques were developed and evaluated for the simultaneous quantification of ezetimibe and propranolol, two commonly prescribed cardiovascular drugs. Both drugs exhibit overlapping native fluorescence, posing a challenge for their selective determination. To address this, chemometric models including partial least squares (PLS) and genetic algorithm-based variable selection (GA) were constructed using a calibration dataset based on a 5 factorial design resulting in 25 synthetic mixtures.

Does Social Media Enhance Rhinoplasty Desire and its Recovery Period: A Saudi Retrospective Study.

Rhinoplasty, which reconstructs the shape and size of the nose, is the most frequently performed cosmetic surgery procedure. Research indicates that social media is the leading influence motivating individuals to undergo rhinoplasty. Thus, we aimed to evaluate the effect of social media on the desire for rhinoplasty and to establish whether (and if so, how) social media enhances the recovery period after rhinoplasty.