4-Week intervention combining kiwifruit consumption and small-sided soccer games improves sleep quality in children with overweight/obesity and pre-existing sleep problems.

Childhood obesity is a global public health concern associated with various health risks, including disrupted sleep patterns. This study investigated the effects of kiwifruit consumption and small-sided soccer games (SSSG) over 4 weeks on sleep patterns in overweight/obese children with sleep problems. Thirty-six participants, aged 8 to 12 years with a body mass index above the 85th percentile, were randomly assigned to one of three groups: SSSG only ( = 12), SSSG-kiwifruit (SSSG-K,  = 12), or control (CG,  = 12).

In Vitro Evaluation, Chemical Profiling, and In Silico ADMET Prediction of the Pharmacological Activities of Root Extract.

L., is a plant with established pharmacological properties, but the root extract (AARE) remains unexplored. The aim of this study was to examine the chemical composition of AARE and assess its biological activity, which included antidiabetic, antibacterial, anticancer, and antioxidant properties.

The impact of technological advancement on culture and society.

Technology plays a pivotal role in shaping cultural identities and practices across the globe. This paper explores the complex relationship between technology and cultural transformation, recognizing both its opportunities and challenges in diverse cultural contexts. We employ key theoretical frameworks, including cultural diffusion, technological determinism and the digital divide, to examine how technological advancements contribute to cultural development.

Congenitally Missing Lateral Incisors: Prioritizing Space Closure Whenever Feasible.

Congenital missing teeth are among the most prevalent dental malformations. Maxillary lateral incisors are particularly prone to agenesis, often missing bilaterally. This condition presented complex challenges for both patients and clinicians.

Effect of cognitive remediation therapy in anorexia nervosa: a systematic review and meta-analysis.

Background: Anorexia nervosa (AN) can significantly affect cognitive well-being. Cognitive remediation therapy (CRT) is regarded as one of the effective treatments for cognitive impairment in some mental illnesses such as schizophrenia, bipolar disorder, and attention deficit. For this reason, this systematic review and meta-analysis aim to assess the effectiveness of CRT in patients with AN.

Comparative Effectiveness of Miswak and Toothbrushing on Dental Plaque and Gingivitis: A Randomized Controlled Trial.

Background/objectives: The miswak, crafted from the tree, is a traditional teeth-cleaning twig that has served as a natural substitute for toothbrushes and toothpaste across diverse regions for centuries. This study aimed to evaluate and compare the effectiveness of miswak and a conventional toothbrush in reducing dental plaque and gingivitis over a two-week period.

Methods: This two-week randomized, single-blind (clinical investigator), two-parallel-arm clinical trial was conducted at Princess Nourah University College of Dentistry (PNUCD).

Uric Acid Levels in Overweight and Obese Children, and Their Correlation With Metabolic Risk Factors.

Background: Obesity is an ongoing medical condition that continues to rise on a global scale. Numerous metabolic disorders, such as type 2 diabetes mellitus, hyperlipidemia, and hyperuricemia, are closely associated with obesity. This particular study aims to investigate the occurrence of hyperuricemia and its association with other metabolic factors among children and adolescents aged 6 to 14 years who are overweight or obese residing in Riyadh, Saudi Arabia.

Prescribing Hydroxyurea in Sickle Cell Disease Patients: The Pattern and Association with Co-Prescribed Medications Used to Manage the Disease Complications.

Hydroxyurea (HU) is an effective medication used to reduce the frequency of painful crises associated with sickle cell disease (SCD). However, data describing its prevalence among SCD patients in the Eastern Region of Saudi Arabia are scarce. This is a multi-center, retrospective, cross-sectional study that aims to investigate the pattern of prescribing HU in SCD patients and to determine the association between prescribing HU and other co-prescribed medications used to manage SCD complications.

Al, P-co-doping and interface engineering synergistically boost the electrocatalytic performance of WS/NiS/NiS nanosheet heterostructure for efficient hydrogen evolution reaction.

The fabrication of earth-abundant electrocatalysts capable of facilitating hydrogen evolution reactions (HER) is essential for creating sustainable hydrogen fuel by water splitting. Here, we present a one-pot hydrothermal approach for producing aluminum and phosphorus co-doped NiS/NiS/WS heterostructure hybrid frameworks on nickel foam. The optimal Al and Al, P/NiWS-b@NF catalyst exhibits high HER activity with overpotentials of 139 and 227 mV at current densities of 10 and 50 mA cm, respectively, thanks to the synergistic effect of the various constituents of the catalyst.

Phytochemical analysis, antioxidant, anticancer, and antibacterial potential of (L.) rhizome.

Willd. () is extremely significant and is utilized extensively in traditional medicine throughout many nations. This study aimed to determine the chemical composition of rhizome extract (AgRE) and to evaluate its antioxidant, anticancer, and antibacterial activities.

Impact of Social Support and Self-Efficacy on Activity of Daily Living among Post-Stroke Patients in Saudi Arabia: A Cross-Sectional Study.

This study employed a cross-sectional design to explore the impact of social support and self-efficacy on activity of daily living (ADL) among post-stroke patients in Saudi Arabia and investigate the mediating role of self-efficacy. Data were collected from 158 post-stroke patients across six healthcare facilities in three regions of Saudi Arabia using convenience sampling, between February 2023 and July 2023. The analysis included descriptive statistics, variance analysis, and linear regression using bootstrap methods.

Anemia among adult patients with diabetes attending King Abdulaziz University Hospital: A retrospective study.

The prevalence of anemia in adults with diabetes is of growing importance due to its impact on overall health and the management of diabetes-related complications. This study aimed to determine the prevalence of anemia among adult patients with diabetes at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. A retrospective study was done on 1208 patients with diabetes >18 years who attended the study setting from 2010 to 2022.

The Recent Trends of Systemic Treatments and Locoregional Therapies for Cholangiocarcinoma.

Cholangiocarcinoma (CCA) is a hepatic malignancy that has a rapidly increasing incidence. CCA is anatomically classified into intrahepatic (iCCA) and extrahepatic (eCCA), which is further divided into perihilar (pCCA) and distal (dCCA) subtypes, with higher incidence rates in Asia. Despite its rarity, CCA has a low 5-year survival rate and remains the leading cause of primary liver tumor-related death over the past 10-20 years.

Distribution of Private Dental Healthcare Facilities in Riyadh City: A GIS-Based Approach.

Background: The dental healthcare private sector in Riyadh city has been growing rapidly over the past few years; however, there is a lack of information on the accessibility and spatial distribution of private dental healthcare facilities (PDHFs) in the area. This study aimed to evaluate the spatial distribution of PDHFs in Riyadh city in relation to population density in each sub-municipality.

Methods: The current information regarding the number, location, and operability of PDHFs in Riyadh city was obtained from the Ministry of Health.

Novel Benzothiadiazole-based Donor-Acceptor Systems: Synthesis, Ultrafast Charge Transfer and Separation Dynamics.

Near-infrared (NIR) absorbing electron donor-acceptor (D-A) chromophores have been at the forefront of current energy research owing to their facile charge transfer (CT) characteristics, which are primitive for photovoltaic applications. Herein, we have designed and developed a new set of benzothiadiazole (BTD)-based tetracyanobutadiene (TCBD)/dicyanoquinodimethane (DCNQ)-embedded multimodular D-A systems (BTD1-BTD6) and investigated their inherent photo-electro-chemical responses for the first time having identical and mixed terminal donors of variable donicity. Apart from poor luminescence, the appearance of broad low-lying optical transitions extendable even in the NIR region (>1000 nm), particularly in the presence of the auxiliary acceptors, are indicative of underlying nonradiative excited state processes leading to robust intramolecular CT and subsequent charge separation (CS) processes in these D-A constructs.

Few-Shot Learning for Medical Image Segmentation Using 3D U-Net and Model-Agnostic Meta-Learning (MAML).

Deep learning has attained state-of-the-art results in general image segmentation problems; however, it requires a substantial number of annotated images to achieve the desired outcomes. In the medical field, the availability of annotated images is often limited. To address this challenge, few-shot learning techniques have been successfully adapted to rapidly generalize to new tasks with only a few samples, leveraging prior knowledge.

Persistent hypocalcemia post total thyroidectomy in a case of Hashimoto's thyroiditis.

Introduction: Thyroidectomy is a surgical procedure commonly employed in the management of thyroid disorders. Complications include, but not limited to, postoperative hypocalcemia. In order to effectively manage hypocalcemia following thyroidectomy, a comprehensive approach is essential.

Corneal myxoma following micro-pulse cyclophotocoagulation in a young female: A case report.

Introduction: Corneal myxoma is a rare benign tumor that can occur in the cornea where the exact cause remains unknown. However, it is thought to be a reactive process that can be caused by corneal infections, ectasia, ocular trauma, or surgery.

Presentation Of Case: In this case report, we describe a 35-year-old-woman who presented with corneal myxoma after micro-pulse cyclophotocoagulation (MPCPC).

Multimodular Wide-Band Capturing Nanohybrids: Role of Carbon Nanotubes in Slowing Charge Recombination in Supramolecular C-BisstyrylBODIPY-(Zinc Porphyrin) Donor-Acceptor Molecular Cleft.

The importance of diameter-sorted single-wall carbon nanotubes (SWCNTs) noncovalently bound to a donor-acceptor , , in prolonging the lifetime of charge-separated states is successfully demonstrated. For this, using a multistep synthetic procedure, a wide-band capturing, multimodular, C-bisstyrylBODIPY-(zinc porphyrin), , was newly synthesized and shown to bind diameter-sorted SWCNTs. The and its supramolecular assemblies were characterized by a suite of physicochemical techniques.

Repositioning of anti-infective compounds against monkeypox virus core cysteine proteinase: a molecular dynamics study.

Monkeypox virus (MPXV) core cysteine proteinase (CCP) is one of the major drug targets used to examine the inhibitory action of chemical moieties. In this study, an in silico technique was applied to screen 1395 anti-infective compounds to find out the potential molecules against the MPXV-CCP. The top five hits were selected after screening and processed for exhaustive docking based on the docked score of ≤ -9.

Aortoiliac occlusion mimicking cauda equina syndrome, a diagnostic dilemma: A case report and review of the literature.

Background: Cauda equina syndrome (CES) is a consequence of a variety of etiologies. CES is most commonly due to compression of the thecal sac and nerve roots by a massive disc herniation. However, it rarely presents secondary to aortic occlusion.

Bioequivalence trials for the approval of generic drugs in Saudi Arabia: a descriptive analysis of design aspects.

Background: This retrospective analysis aimed to comprehensively review the design and regulatory aspects of bioequivalence trials submitted to the Saudi Food and Drug Authority (SFDA) since 2017.

Methods: This was a retrospective, comprehensive analysis study. The Data extracted from the SFDA bioequivalence assessment reports were analyzed for reviewing the overall design and regulatory aspects of the successful bioequivalence trials, exploring the impact of the coefficient of variation of within-subject variability (CVw) on some design aspects, and providing an in-depth assessment of bioequivalence trial submissions that were deemed insufficient in demonstrating bioequivalence.