Hormonal profile in children with isolated hypospadias associates better with comprehensive score of local anatomical factors as compared to meatal location or degree of chordee.

Background: To evaluate if hormonal profile of children with isolated hypospadias (IH) associates better with comprehensive local anatomical factor score (LAFS) than with clinically adjudged urethral meatus location or severity of chordee/k.j.

Material And Methods: Ninety-nine children with IH were enrolled, as per inclusion criteria.

Children with isolated hypospadias have different hormonal profile compared to those with associated anomalies.

Aim: The objective of this study is to compare the hormonal profile of children with isolated hypospadias to controls and hypospadiacs with associated anomalies.

Study Design: Prospective observation at a tertiary referral hospital.

Study Subjects: One hundred consecutive children (0-12 years) with isolated hypospadias (H), 23 with hypospadias and associated anomalies (HO).