Publications by authors named "Alpi P"
Background And Purpose: Data on immunoresponse after SARS-CoV-2 vaccines for patients treated with exclusive radiotherapy (RT) are scarce. Since RT may affect the immune system, we conducted the MORA trial (Antibody response and cell-mediated immunity of MOderna mRNA-1273 vaccine in patients treated with RAdiotherapy).
Materials And Methods: Data regarding humoral and cellular immune response of patients treated with RT were prospectively collected after the second and third dose of mRNA vaccines.
Purpose: The robustness of surface-guided (SG) deep-inspiration breath-hold (DIBH) radiotherapy (RT) for left breast cancer was evaluated by investigating any potential dosimetric effects due to the residual intrafractional motion allowed by the selected beam gating thresholds. The potential reduction of DIBH benefits in terms of organs at risk (OARs) sparing and target coverage was evaluated for conformational (3DCRT) and intensity-modulated radiation therapy (IMRT) techniques.
Methods: A total of 192 fractions of SGRT DIBH left breast 3DCRT treatment for 12 patients were analyzed.
Article Synopsis
- This study looked at how in vivo dosimetry (IVD) helps manage risks during lung cancer treatments that use a special kind of radiation.
- They checked the treatment results for 93 patients in two phases to find and fix mistakes.
- By making better procedures and checking things carefully, they saw fewer errors and improved the accuracy of the treatments.
Purpose: To compare two left breast cancer patient cohorts (tangential vs. locoregional deep-inspiration breath-hold - DIBH treatment) with different predefined beam gating thresholds and to evaluate their impact on motion management and DIBH stability.
Methods: An SGRT-based clinical workflow was adopted for the DIBH treatment.
Purpose: To analyze results from three years of in vivo transit EPID dosimetry of abdominal and pelvic stereotactic radiotherapy and to establish tolerance levels for routine clinical use.
Material: 80 stereotactic VMAT treatments (152 fractions) targeting the abdomen or pelvis were analyzed. In vivo 3D doses were reconstructed with an EPID commercial algorithm.
Aim: To quantify the variability between radiation oncologists (ROs) when outlining axillary nodes in breast cancer.
Material And Methods: For each participating center, three ROs with different levels of expertise, i.e.