Publications by authors named "Alpha Barrie"

Article Synopsis
  • Enhanced Disease Susceptibility 1 (EDS1) is crucial for plant immune responses, and six novel EDS1 genes were identified in Brassica napus, with four responding specifically to clubroot infection.
  • Overexpression of Bna-EDS1 enhances resistance to this disease by activating defense genes, while RNA interference (RNAi) leads to increased susceptibility, demonstrating its role in immune signaling.
  • Bioinformatics revealed important connections between Bna-EDS1 and hormonal stress responses, indicating that EDS1 may utilize the salicylic acid pathway to combat clubroot disease in rapeseed.
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Background: Autism spectrum disorders (ASDs) are diagnosed by social communication difficulties strong, narrow interests, and repetitive stereotyped behavior. An apparently-elevated prevalence of ASD at a major UK hemophilia center warranted investigation.

Objectives: To screen boys with hemophilia for difficulties in social communication and executive function and identify the prevalence and risk factors for ASD.

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 The efficacy and safety of wilate (human von Willebrand factor/coagulation factor VIII) in patients with von Willebrand disease (VWD) has been demonstrated in clinical trials. Here, we present real-world data on the use of wilate for the routine care of patients with VWD.  The objectives of this observational, prospective, phase 4 study were to evaluate the safety, tolerability, and effectiveness of wilate in on-demand treatment of bleeding episodes (BEs), long-term prophylaxis, and surgical prophylaxis among patients with any type of VWD.

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