Publications by authors named "Alparslan Cansiz"

Article Synopsis
  • The study looked at how social support, coping skills, anxiety, and depression affected COVID-19 patients compared to healthy people.
  • COVID-19 patients felt they had more social support and better coping skills, but their anxiety and depression levels were similar to those without COVID-19.
  • The research suggests that using good coping strategies and having strong social support can help lower anxiety and depression, and more studies are needed to see how these factors help people recover from the effects of COVID-19.
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Objective: High-arched palate is more frequent in schizophrenia and bipolar disorder (BD). Upto 40% of patients develop schizophrenia in 22q11.2 Deletion Syndrome manifested with cleft lip and palate, which originate from the first pharyngeal arch in embryo.

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Introduction: Studies exploring the theory of mind (ToM) in adults with Attention/Deficit Hyperactivity Disorder (ADHD), have tended to result in mixed findings. The contribution of neuropsychologic functions to ToM has not been investigated yet in adults with ADHD. The aim of this study was to investigate ToM abilities and the role of attention and executive functions in ToM of adults with ADHD.

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Background: The role of sex steroids in bipolar disorder (BD) has been demonstrated in adults. We aimed to evaluate the 2D:4D ratio, which indirectly reflects prenatal sex steroids, in BD. Another purpose of this study was to determine the relationship between clinical features, especially lithium response, and digit ratio.

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Objective: The purpose of this study is to evaluate the reliability and validity of the Turkish Version of the Bipolar Spectrum Diagnostic Scale (BSDS).

Method: The study was carried out with 130 patients diagnosed with bipolar I disorder, 15 patients diagnosed with bipolar II disorder, and 38 patients diagnosed with major depressive disorder attending the outpatient psychiatry departments of the Bakırköy Prof. Dr.

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Article Synopsis
  • There is limited evidence on clinical predictors for lithium treatment response in bipolar disorder, prompting this study to explore the connection between treatment outcomes and specific GSK-3β gene polymorphisms.
  • Using Lithium treatment response scale (LTRS) scores from 100 type I bipolar patients, along with genomic DNA analysis through PCR, researchers found a significant association only with the GSK-3β rs17183890 AG genotype.
  • The findings suggest this specific polymorphism could help predict individual responses to lithium, highlighting the need for further research on larger populations to refine personalized treatment strategies.
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Introduction: In the literature, the relationship between appetite regulating peptides and alcohol craving is on the debate.

Aim: This study aims to investigate serum level of NUCB2/nesfatin-1, which is discovered as appetite-related neuropeptide, in patients with alcohol dependence who were in craving and abstaining phase and to compare with healthy controls.

Settings And Design: Research, Treatment, and Training Center for Alcohol and Substance Dependence, (AMATEM) Bakirkoy Training and Research Hospital for Psychiatry Neurology and Neurosurgery, Istanbul, case-control and prospective study design were used.

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In the present study we investigated the involvement of inflammatory cells and their ratios as inflammation markers in Bipolar Disorder. We have enrolled 61 manic, 55 euthymic patients and 54 control subjects to the study. Neutrophil-lymphocyte and platelet-lymphocyte ratios were found significantly higher in both manic and euthymic patients compared to control group.

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We investigated serum total oxidative and anti-oxidative status in manic patients. Group1 was formed as ECT+antipsychotic, group2 was antipsychotic and healthy volunteers as group3. The anti-oxidative status was significantly lower in group1 than group3.

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