Optimizing tacrolimus therapeutic drug monitoring in Tunisian kidney transplant recipients: exploring the variability in bioavailability and the correlation between pharmacokinetic parameters.

Objectives: While the existing literature extensively covers the topic of tacrolimus variability, it remains crucial to gather data that are tailored to the Tunisian population. Our primary goal was to assess the variability in tacrolimus bioavailability using the Cp(0)/weight dosage ratio in Tunisian kidney transplant patients. We also aimed to determine the correlations between blood trough level (Cp(0)) and the area under the concentration-time curve (AUC0-12 h) in this cohort.

Combined Plyometric and Short Sprint Training in U-15 Male Soccer Players: Effects on Measures of Jump, Speed, Change of Direction, Repeated Sprint, and Balance.

This study examined the effect of 8 weeks of biweekly combined plyometric and short sprint training into the typical within-season training schedule of youth male soccer players. Participants were allocated at random to an experimental group (EG; = 17, age: 14.6 ± 0.

An 8-Week Program of Plyometrics and Sprints with Changes of Direction Improved Anaerobic Fitness in Young Male Soccer Players.

This study examined the effects of 8 weeks of twice-weekly combined plyometric and sprint with change-of-direction (CPSCoD) training into habitual training regimes of young male soccer players. Participants were randomly allocated to an experimental group ( = 17, age: 14.6 ± 0.

Effects of Combined Plyometric and Short Sprints Training on Athletic Performance of Male U19 Soccer Players.

This project investigated adding 8 weeks of biweekly plyometric and short sprints training into standard training in elite youth soccer players. An experimental group (EG, = 18, age: 17.6 ± 0.

Neuromuscular Adaptations and Enhancement of Physical Performance in Female Basketball Players After 8 Weeks of Plyometric Training.

The aim of this study was to examine the effects of an 8-week in-season plyometric training (PT) program on the physical performance and neuromuscular adaptations of female basketball players. Twenty-seven elite female basketball players (aged 21.0 ± 2.

Effects of Elastic Band Based Plyometric Exercise on Explosive Muscular Performance and Change of Direction Abilities of Male Team Handball Players.

This study examined the effects of incorporating 8 weeks of bi-weekly lower limb elastic band based loaded plyometric training into the in-season regimen of junior handball players. Participants were assigned between control ( = 15, age: 18.1 ± 0.

The effect of music on short-term exercise performance during the different menstrual cycle phases in female handball players.

The present study aimed to evaluate the effect of music on short-term exercise performance during the different menstrual cycle phases (MCP). In different MCP (i.e.

Field Tests of Performance and Their Relationship to Age and Anthropometric Parameters in Adolescent Handball Players.

Handball performance is influenced by age, anthropometric characteristics, technical skills, tactical understanding, and physical abilities. The aims of this study were (i) to determine differences in anthropometric characteristics and physical performance between adolescent handball players across age categories, and (ii) to determine which anthropometric and maturity variables have the greatest relative importance in fitness for this sport. Seventy-nine male handball players drawn from a team in the elite Tunisian Handball league [U18 ( = 10); U17 ( = 12); U16 ( = 17); U15 ( = 18); and U14 ( = 22)] volunteered for the investigation.

Effects of a Combined Upper- and Lower-Limb Plyometric Training Program on High-Intensity Actions in Female U14 Handball Players.

Purpose: To analyze the effects of a 9-week plyometric training program on the sprint times (5, 10, 20, and 30 m), change-of-direction speed (modified T test and modified Illinois test), jumping (squat jump, countermovement jump, countermovement jump with arms, and horizontal 5-jump test), upper-body strength (right and left handgrip, back extensor strength, and medicine ball throw), and balance (Y and stork balance tests) of female handball players.

Methods: Athletes were randomly divided into experimental (n = 21; age = 13.5 [0.

Effects of an 8-Week In-Season Upper Limb Elastic Band Training Programme on the Peak Power, Strength, and Throwing Velocity of Junior Handball Players.

Background:  Team handball is an intense sport with special requirements on technical and tactical skills as well as physical performance. The ability of handball players to make repeated powerful muscular contractions in pushing and throwing the ball is crucial to success.

Objective:  This study investigated the effects of elastic band training on upper body peak power output, ball throwing velocity, and local muscle volume of junior handball players.

Monitoring Conformational Changes in an Enzyme Conversion Inhibitor Using Pure Shift Exchange NMR Spectroscopy.

We report the acquisition of 2D NMR EXSY spectra with ultrahigh resolution, which allows for probing the slow conformational exchange process in a pharmaceutical compound. The resolution enhancement is achieved by implementing interferogram based PSYCHE homonuclear decoupling to generate a pure shift proton spectrum along the direct domain of the resulting data. The performance of this pure shift EXSY pulse sequence is compared to the standard experiment recorded under identical conditions.

Effects of Short-Term In-Season Weightlifting Training on the Muscle Strength, Peak Power, Sprint Performance, and Ball-Throwing Velocity of Male Handball Players.

Hermassi, S, Schwesig, R, Aloui, G, Shephard, RJ, and Chelly, MS. Effects of short-term in-season weightlifting training on the muscle strength, peak power, sprint performance, and ball-throwing velocity of male handball players. J Strength Cond Res 33(12): 3309-3321, 2019-This study analyzed the effects of in-season weightlifting training, conducted biweekly for 12 weeks.

Effects of Combined Plyometric and Short Sprint With Change-of-Direction Training on Athletic Performance of Male U15 Handball Players.

Hammami, M, Gaamouri, N, Aloui, G, Shephard, RJ, and Chelly, MS. Effects of combined plyometric and short sprint with change-of-direction training on athletic performance of male U15 handball players. J Strength Cond Res 33(3): 662-675, 2019-This study examined the effects of combined plyometric and change-of-direction training (CPT) on selected measures of performance (repeated-sprint T-test [RSTT], sprint performance [5, 10, 20, and 30 m], change-of-direction tests [modified Illinois test and T-half test], squat jump, countermovement jump, countermovement jump with aimed arms 5-jump test, Y-balance test, Stork balance test, and 20-m shuttle run) in male U15 handball players.

Effects of an 8-Week In-Season Elastic Band Training Program on Explosive Muscle Performance, Change of Direction, and Repeated Changes of Direction in the Lower Limbs of Junior Male Handball Players.

Aloui, G, Hammami, M, Fathloun, M, Hermassi, S, Gaamouri, N, Shephard, RJ, and Chelly, MS. Effects of an 8-week in-season elastic band training program on explosive muscle performance, change of direction, and repeated changes of direction in the lower limbs of junior male handball players. J Strength Cond Res 33(7): 1804-1815, 2019-The aim of this study was to examine the effects of incorporating 8 weeks of biweekly lower-limb elastic band training (knee and hip extension) into the in-season regimen of junior handball players.

Effects of a Complex Strength-Training Program on Athletic Performance of Junior Female Handball Players.

Purpose: To analyze the effects of complex strength training on explosive muscle performance of junior female handball players.

Methods: Subjects were arbitrarily divided between an experimental group (n = 14) and a control group (n = 14). Training sessions and matches were performed together, but during the 10-wk intervention, the experimental group replaced part of the regular regimen with complex strength training.