Thermochemical Analysis of Ammonia Gas Sorption by Struvite from Livestock Wastes and Comparison with Biochar and Metal-Organic Framework Sorbents.

Struvite-bearing solids from swine (S) and dairy (D) wastewater, heat-treated to 150-300 °C, were evaluated as ammonia gas (NH(g)) sorbents and compared to biochar (BC) and a metal-organic framework (MOF). Simultaneous thermal analysis-pulse thermal analysis-Fourier-transform infrared spectroscopy (STA-PTA-FTIR) was used to determine sorption capacity, reversibility, thermodynamics, and kinetics. For wastewater-derived sorbents, S solids heated to 150 °C (S-150) had the highest NH(g) sorption capacity (47.

Anti-inflammatory and protective effects of MT-031, a novel multitarget MAO-A and AChE/BuChE inhibitor in scopolamine mouse model and inflammatory cells.

Previous study demonstrated that the novel multitarget compound, MT-031 preserved in one molecule entity the beneficial properties of its parent drugs, rasagiline and rivastigmine, and exerted high dual potencies of monoamine oxidase-A (MAO-A) and cholinesterase (ChE) inhibition in acute-treated mice and neuroprotective effects against HO-induced neurotoxicity in human neuroblastoma SH-SY5Y cells. The present study aimed to further investigate the anti-inflammatory and protective effects of MT-031 in scopolamine mouse model and inflammatory cell cultures. Our findings demonstrated that once daily chronic administration of MT-031 (5-10 mg/kg) to mice antagonized scopolamine-induced memory and cognitive impairments, displayed brain selective MAO-A and AChE/BuChE inhibition, increased the levels of striatal dopamine (DA), serotonin (5-HT) and norepinephrine and prevented the metabolism of DA and 5-HT.