Background: The majority of current medical CBIR systems perform retrieval based only on "imaging signatures" generated by extracting pixel-level quantitative features, and only rarely has a feedback mechanism been incorporated to improve retrieval performance. In addition, current medical CBIR approaches do not routinely incorporate semantic terms that model the user's high-level expectations, and this can limit CBIR performance.
Method: We propose a retrieval framework that exploits a hybrid feature space (HFS) that is built by integrating low-level image features and high-level semantic terms, through rounds of relevance feedback (RF) and performs similarity-based retrieval to support semi-automatic image interpretation.