Publications by authors named "Alok Thakur"

Arsenic (As), a geogenic legacy pollutant can be present in environmental matrices (water, soil, plants, or animal) in two redox states (As(III) or As(V)). In the present study, charged mono- and di-amino functionalized triethoxy and methoxyorganosilane (TT1 and TT2- 1% and 5%) were impregnated with quartz sand particles for the treatment of As polluted water. Spectroscopic characterization of organosilane treated sand (STS) indicated the co-existence of minerals (Mg, Mn, Ti), amide, and amidoalkyl groups, which implies the suitability of silanized materials as a metal(loids) immobilization agent from water.

View Article and Find Full Text PDF

Extrarenal extracranial malignant rhabdoid tumour (MRT) is a rare and highly aggressive tumour representing <1% of paediatric soft tissue malignancies. Only a few cases of MRT of the thigh arising from the sciatic nerve have been reported in medical literature to date. A 5-year-old girl presented with progressively increasing painless lump in the posterior aspect of the left thigh.

View Article and Find Full Text PDF

The ongoing COVID-19 pandemic increases the consumption of antimicrobial substances (ABS) due to the unavailability of approved vaccine(s). To assess the effect of imprudent consumption of ABS during the COVID-19 pandemic, we compare the 2020 prevalence of antidrug resistance (ADR) of Escherichia coli (E. coli) with a similar survey carried out in 2018 in Ahmedabad, India using SARS-CoV-2 gene detection as a marker of ABS usage.

View Article and Find Full Text PDF

Arsenic (As), a geogenic and extremely toxic metalloid can jeopardize terrestrial and aquatic ecosystems through environmental partitioning in natural soil-water compartment, geothermal and marine environments. Although, many researchers have investigated the decontamination potential of different mesoporous engineered bio sorbents for a suite of contaminants, still the removal efficiency of various pyrolyzed agricultural residues needs special attention. In the present study, rice straw derived biochar (RSBC) produced from slow pyrolysis process at 600 °C was used to remove As (V) from aqueous medium.

View Article and Find Full Text PDF

Increased concern has recently emerged pertaining to the occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in aquatic environment during the current coronavirus disease 2019 (COVID-19) pandemic. While infectious SARS-CoV-2 has yet to be identified in the aquatic environment, the virus potentially enters the wastewater stream from patient excretions and a precautionary approach dictates evaluating transmission pathways to ensure public health and safety. Although enveloped viruses have presumed low persistence in water and are generally susceptible to inactivation by environmental stressors, previously identified enveloped viruses persist in the aqueous environment from days to several weeks.

View Article and Find Full Text PDF
Article Synopsis
  • - The paper presents an autonomous disinfection tunnel designed to sanitize surfaces potentially contaminated with COVID-19, suitable for high-traffic public areas like airports and schools.
  • - The tunnel features two chambers employing three disinfection methods: a disinfectant spray in Chamber 1 and exposure to hot air and far-ultraviolet C rays in Chamber 2, enhancing virus neutralization efficacy.
  • - Developed through a collaboration between Technopark@iitk and ALIMCO under Indian government ministries, this innovative solution is called the 'Techno Advanced Disinfection Tunnel' (TADT).
View Article and Find Full Text PDF

A new series of 3-(4-substituted phenyl)-1-(4-(4,6-dimethyl-6H-1,3-thiazin-2-yl)phenylsulfonyl)-1-substituted urea (5a-o) was synthesized by an effectual route via sulfonylcarbamates and explores the novel site for substitution in sulfonylurea as well as the way of thiazine can be prepared. The molecules were established by elemental analysis and spectroscopic viz. IR, (1)H NMR, (13)C NMR and MS techniques.

View Article and Find Full Text PDF

A newer series of 1-(4-substitutedphenyl)-3-(4-((2,4-dioxothiazolidin-5-lidene)methyl)phenyl sulfonyl)urea/thiourea (4a-l) were synthesized for their anticonvulsant activity. The activity is attributed to its potential to restrain astrocytic Na+, 2HCl, and K+ co-transport similar to torasemide which has sulfonylurea in its structure. Torasemide having the similar action as the furosemide that obstructs kainic acid-induced electrical discharges observed from cortex and it has neuroprotective agents, for instance antagonizing the N-methyl-D-aspartate (NMDA) and non-NMDA receptors for evaluating antiepileptic activity.

View Article and Find Full Text PDF

In the present study a series of new N(4)-(4-substituted benzylidene)-N(1)-([1,3,4]thiadiazino [6,5-b]indol-3-yl)semicarbazide (1-6), N(4)-([1,3,4]thiadiazino[6,5-b]indol-3-yl)-N(1)-(1-(4-substituted phenyl)ethylidene)semicarbazide (7-10), N(4)-([1,3,4]thiadiazino[6,5-b]indol-3-yl)-N(1)-((4-substituted phenyl)(phenyl)methylene) semicarbazide. (11-14) have been synthesized from isatin and thiosemicarbazide through multiple steps to meet structural necessities for the anticonvulsant activity. All the newly prepared compounds were characterized by spectral techniques like FT-IR, (1)H and (13)C NMR, EI-MS and elemental analysis.

View Article and Find Full Text PDF

Filariasis is result of parasitic infection caused by three specific kinds of round worm. Lymphatic filariasis is found in under developed region of South America, Central Africa, pacific and Caribbian. It has been found for centuries, with main symptoms as elephant like swelling of the arms, legs and genitals.

View Article and Find Full Text PDF