Publications by authors named "Alok Sen"
Purpose: To evaluate rural community-based eye care models from the perspective of community ophthalmology experts and suggest sustainable technological solutions for enhancing rural eye care delivery.
Methods: A semi-structured descriptive survey, using close-ended and open-ended questions, was administered to the experts in community ophthalmology sourced through purposive sampling. The survey was self-administered and was facilitated through online platforms or in-person meetings.
Purpose: To evaluate the role of repeated intravitreal methotrexate as an adjunct to pars plana vitrectomy in the management of rhegmatogenous retinal detachment with choroidal detachment.
Method: The authors compared anatomical and visual outcomes of rhegmatogenous retinal detachment with choroidal detachment eyes that underwent pars plana vitrectomy with (Group B) or without repeated intravitreal methotrexate (Group A).
Results: The study included 25 eyes of 25 patients, 16 eyes in Group A and nine in Group B.
Purpose: The knowledge and attitude of participants toward clinical trials (CTs) are a key determinant in successful recruitment and retention. This study aimed to evaluate knowledge and awareness-attitude among the recruited CT participants about CTs.
Methods: This was a cross-sectional face-to-face survey comprising CT participants involved in the past or currently a part of a CT during this study within the Indian Ophthalmology Clinical Trial Network (IOCTN).
Mobile battery blast injuries: An emerging ocular health hazard in children.
Indian J Ophthalmol
December 2023
Purpose: To assess clinical features, visual outcomes, and setting of mobile battery blast-induced eye injuries in children.
Methods: Retrospective case sheets of children with mobile battery blast injuries were reviewed at a tertiary eye care center from January 2015 to March 2022. We noted the mode of injury, battery status, and clinical presentation and analyzed the treatment outcomes.
Purpose: To assess the diagnostic performance of two chatbots, ChatGPT and Glass, in uveitis diagnosis compared to renowned uveitis specialists, and evaluate clinicians' perception about utilizing artificial intelligence (AI) in ophthalmology practice.
Methods: Six cases were presented to uveitis experts, ChatGPT (version 3.5 and 4.
Purpose: Advances in patient treatment depend heavily on clinical trials (CTs). Patient volunteers for CT are tougher to recruit and retain. In order to administer CTs effectively, it is necessary to comprehend how the public views and perceives participating in them.
View Article and Find Full Text PDFIntroduction: Accurate diagnosis and timely management are vital for favorable uveitis outcomes. Artificial Intelligence (AI) holds promise in medical decision-making, particularly in ophthalmology. Yet, the diagnostic precision and management advice from AI-based uveitis chatbots lack assessment.
View Article and Find Full Text PDFPurpose: To describe a professionalism survey tool and its use to assess knowledge of medical professionalism in ophthalmology training programs in Central India.
Settings And Design: Multi-center survey study.
Methods: A validated 33-question, scenario-based survey addressing professionalism attributes was administered at five centers in central India.
Purpose: The purpose of the study was to evaluate the knowledge and perception of health-care professionals (HCPs), such as doctors/surgeons, pharmacists, nurses, optometrists, and lab technicians, on clinical trials (CTs) in India.
Methods: The study was a pan-Indian cross-sectional survey initiated by the Indian Ophthalmology Clinical Trial Network (IOCTN) by using a previously validated questionnaire for three months of data collection. An online survey was used to record information regarding demographics, CT knowledge, and CT perception among HCPs.
In the current literature, clinical registry cohorts related to ocular inflammation are few and far between, and there are none involving multi-continental international data. Many existing registries comprise administrative databases, data related to specific uveitic diseases, or are designed to address a particular clinical problem. The existing data, although useful and serving their intended purposes, are segmented and may not be sufficiently robust to design prognostication tools or draw epidemiological conclusions in the field of uveitis and ocular inflammation.
View Article and Find Full Text PDFPurpose: To compare the outcomes of immediate pars plana vitrectomy (PPV) and tap and inject in eyes with postcataract surgery endophthalmitis.
Methods: Patients presenting with acute postcataract surgery endophthalmitis and visual acuity between ≥ hand movement and <6/18 were randomized to receive either PPV (Group A) or tap and inject (Group B).
Results: There were 26 and 31 eyes in Group A and Group B, respectively.
Introduction: The incidence of post vitrectomy endophthalmitis (PVE) is reported to be between 0.02 and 0.84%.
View Article and Find Full Text PDFPurpose: To report a case of disseminated TB presenting as ciliary body and thyroid mass lesions.
Case Report: A 17-year-old male patient presented with a thyroid mass and blurring of vision in the left eye. A diagnosis of ciliary body granuloma was made.
Article Synopsis
- The study aimed to assess changes in central macular thickness (CMT) and subfoveal choroidal thickness (SFCT) in kids after cataract surgery using spectral domain optical coherence tomography (SD-OCT).
- It followed 90 pediatric patients over three months, measuring CMT and SFCT at various postoperative intervals, noting significant initial increases in these measurements, particularly in patients with traumatic cataracts.
- Despite these anatomical changes, there was no impact on visual outcomes, indicating that while cataract surgery can lead to inflammatory changes, they don't negatively affect vision, and the additional step of posterior capsulotomy does not cause further significant changes.
Endogenous endophthalmitis (EE) is an uncommon but potentially devastating ocular infection involving the inner layers of the eye. The global incidence of EE is on the rise. Common ocular signs and symptoms associated with EE include conjunctival injection, ocular pain, and reduced visual acuity.
View Article and Find Full Text PDFPurpose: In this case report, we describe the clinical features and treatment outcomes of bilateral optic neuritis developing after the administration of the first dose ChAdOx1_nCoV-19 (Covishield) vaccine in a previously healthy young immunocompetent male.
Study Design: Case report.
Results: A 35-year-old healthy male, presented with sudden decrease in vision which was progressive in nature.
Purpose: : To analyze the anatomical and visual outcomes of microincision vitrectomy surgery (MIVS) with silicone oil tamponade in eyes having coloboma-related retinal detachment (RD) and evaluate the risk factors for recurrence of RD.
Methods: : This was a retrospective, multicentric analysis of eyes having coloboma RD undergoing MIVS with silicone oil tamponade between March 2010 and July 2018.
Results: : We evaluated 148 eyes of 144 patients.
Sympathetic ophthalmia is a rare, bilateral, granulomatous, panuveitis following penetrating trauma or surgery to one eye. Clinical presentation commonly occurs within the first year of trauma occurrence but can be delayed by several years. It manifests as acute/chronic granulomatous uveitis with yellowish-white choroidal lesions or Dalen-Fuchs nodules.
View Article and Find Full Text PDFPurpose: To correlate optical coherence tomography (OCT)-based morphological patterns of diabetic macular edema (DME), biomarkers and grade of diabetic retinopathy (DR) in patients with various stages of chronic kidney disease (CKD) secondary to diabetes.
Design: Multicentric retrospective cross-sectional study was conducted at seven centers across India.
Methods: Data from medical records of patients with DME and CKD were entered in a common excel sheet across all seven centers.