Interleukin-10 levels in azithromycin-induced cardiac damage and the protective role of combined selenium and vitamin E treatment.

Azithromycin is a broad-spectrum antibiotic commonly used to treat bacterial infections but is associated with adverse cardiac effects, including oxidative damage and myocardial inflammation. This study aims to explore the histopathological and biochemical changes, including serum interleukin-10 levels, induced by azithromycin in the hearts of male albino rats and to evaluate the protective role of combined selenium and vitamin E treatment. Forty rats were divided into four groups: a control group, an azithromycin treatment group, selenium and vitamin E treatment group, and a combined treatment group receiving both azithromycin, selenium, and vitamin E.

Impact of co-administration of apricot kernels and caffeine on adult male diabetic albino rats.

The purpose of this study is to evaluate the impacts of apricot kernels and caffeine on blood glucose, lipid profile, insulin secretion, and antioxidant effect in diabetic rats. Forty adult male albino rats were divided into five groups: normal control, diabetic control, diabetic rats treated with apricot kernels, diabetic rats treated with caffeine, and diabetic rats treated with apricot kernels plus caffeine. Fasting samples were collected at the end of the study for analysis, and pieces of liver and pancreatic tissues were removed for histological analysis.