This review describes the germ cell neoplasms that are malignant and most commonly associated with several types of gonadal dysgenesis. The most common neoplasm is gonadoblastoma, while others including dysgerminomas, yolk-sac tumors and teratomas are rare but can occur. The purpose of this review is to evaluate the incidences of these abnormalities and the circumstances surrounding these specific tumors.
View Article and Find Full Text PDFPurpose: To evaluate the impact of bariatric surgery on the gestational outcomes.
Materials And Methods: Retrospective study of pregnant women hospitalized for delivery in the maternity in Curitiba, Brazil, who had a body mass index (BMI) greater than or equal to 30 kg/m and/or who had undergone bariatric surgery. Interviews were performed, and the patients' medical records and antenatal information cards were evaluated.
This review aimed to look into agents and mechanisms characterized as endocrine disrupting chemicals (EDCs). These agents are known to cause several harmful effects to the reproductive system of women and wildlife. There is a wide range of chemicals, developed for commercial use mainly in agriculture, which may cause endocrine disruption.
View Article and Find Full Text PDFObjective: To study the prevalence and the clinical and demographic associations of hypovitaminosis D in pregnant women from southern Brazil.
Methods: In this cross-sectional study, pregnant women attending prenatal care at two university clinics in Curitiba, Brazil, were investigated for clinical and demographic data and for serum levels of vitamin D, calcium, and parathyroid hormone. Data were collected during summer (January 26 to March 4, 2016) or winter (July 28 to August 31, 2016).
Hand-food-genital syndrome (HFGS) is a rare genetic condition. This report describes the cases of two patients, aged 33 and 15, presenting related somatic abnormalities. HFGS stems from an autosomal anomaly linked to the HOXA 13 gene.
View Article and Find Full Text PDFBackground: The polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women at childbearing age. Metabolic syndrome is present from 28% to 46% of patients with PCOS. Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic expression of metabolic syndrome.
View Article and Find Full Text PDFRev Bras Ginecol Obstet
March 2015
Purpose: To assess fatigue and quality of life in disease-free breast cancer survivors in relation to a sample of age-matched women with no cancer history and to explore the relationship between fatigue and quality of life.
Methods: A cross-sectional study was conducted in a sample of 202 consecutive disease-free Brazilian breast cancer survivors, all of whom had completed treatment, treated at 2 large hospitals. The patients were compared to age-matched women with no cancer history attending a primary health care center.
This paper aimed to report a series of 19 cases of uterus didelphys associated with obstructed hemivagina and ipsilateral renal agenesis. This retrospective descriptive observational study included the medical records of 19 patients seen at the Endocrinology Gynecology Sector of the Obstetrics and Gynecology Department of the Federal University of Paraná, and focused on clinical data, complementary exams, patient management, and follow-up. From the 229 patients with genital anomalies seen between 1984 and 2009, 19 (8.
View Article and Find Full Text PDFRev Bras Ginecol Obstet
October 2012
Purposes: To assess the quality of life of breast cancer survivors compared to a sample of age-matched healthy women.
Methods: A cross-sectional design was conducted on 199 consecutive breast cancer survivors, one year or more after diagnosis, treated at two large hospitals. The patients were compared to age-matched healthy women consisting of employees and volunteers of the two hospitals.
Support Care Cancer
August 2012
Purpose: Fatigue is a phenomenon that may persist for years after completion of adjuvant therapy, and is one of the most frequent symptoms associated with breast cancer survivors. The purposes of this study were to investigate the occurrence of fatigue in disease-free breast cancer survivors after treatment, to identify variables associated with fatigue, and to evaluate the impact of fatigue on health-related quality of life.
Methods: A cross-sectional study was conducted on 202 consecutive women diagnosed with in-situ to Stage III breast cancer attending in outpatient facilities of two large hospitals, one year or more after diagnosis.
There is little information about the knowledge and attitudes of physicians regarding oral care. This study aimed to assess the knowledge and attitudes of obstetricians about the relationship between periodontal disease and preterm/low birth weight. A questionnaire was emailed to members of the Brazilian Federation of Gynecology and Obstetrics (FEBRASGO).
View Article and Find Full Text PDFPurpose: the purpose of this research was to evaluate the morphological aspects and vasculature of the corpus luteum (CL) based on ultrasound parameters during early pregnancy and to assess their relationship with early pregnancy loss.
Methods: this was a prospective cohort study of 90 pregnant patients between 6 and 8 weeks plus 6 days weeks of gestation. We included women at low risk, without acute or chronic systemic disease and with spontaneous conception.
Objective: Compare levels of androgens and bone mineral density (BMD) of ovariectomized (OVX) and non-ovariectomized (NOVX) postmenopausal women. Forty women, 20 OVX and 20 NOVX, (53.9 +/- 4 years) were selected.
View Article and Find Full Text PDFContext: Successful liver transplantation not only treats the underlying liver disease but also restores libido and fertility in female recipients. Although reports of successful pregnancy after liver transplantation continue to increase, these pregnancies are considered of high-risk because they are associated with increase maternofetal morbidity.
Evidence Acquisition: A MEDLINE search (1978-2007) was conducted using the terms 'liver transplantation', 'pregnancy', 'immunosuppressive agents', 'sexual function'.
To determine the relationship between human papillomavirus (HPV) and endometrial carcinogenesis by comparing data from women with endometrial carcinoma to those of women with normal endometrial tissue. The survey was conducted for 100 women (50 with endometrial carcinoma and 50 with normal endometrial tissue) through HPV-DNA testing of paraffin-embedded endometrial tissue sections by polymerase chain reaction. Age, cigarette consumption, squamous differentiation and tumor grade, endometrium trophism, and HPV types detected in endometrial tissues were studied.
View Article and Find Full Text PDFThe present survey was conducted among medical students and physicians affiliated to the Federal University of Paraná, Curitiba, Brazil, between August 2006 and December 2007. 252 individuals responded to a questionnaire composed of 13 items regarding their individual status and their personal knowledge of the HPV vaccine properties. The data analysis that was carried out using chi-square test showed that 79.
View Article and Find Full Text PDFPurpose: This study was conducted to verify the predictive value of epiphyseal ossification center measurements in estimating gestational age.
Methods: Women with singleton pregnancies of 30-40 weeks gestation (n = 377) were enrolled in this prospective study. The distal femoral, proximal tibial, and proximal humeral ossification centers were identified and measured.