Publications by authors named "Almerio N Filho"
Article Synopsis
- Cutaneous leishmaniasis (CL) is linked to a positive skin test (LST) that indicates the presence of immune T cells specific to disease antigens, with this study focusing on the differences between LST+ and LST- patients.
- LST- patients showed larger lesions, a longer duration of illness, more treatment failures with meglumine antimonate, and higher healing times compared to LST+ patients.
- The study suggests that LST- patients have an impaired Th1 immune response, characterized by higher parasite loads, lower granuloma frequency, increased CD8+ T cells, and excess Granzyme B production, leading to more severe disease.
