Publications by authors named "Almerinda Maria do Rego Silva"

Article Synopsis
  • - This study aimed to investigate the effects of SARS-CoV-2 infection on Brazilian patients with Inborn Errors of Immunity (IEI), focusing on their clinical outcomes and factors influencing the infection.
  • - In a multicenter study of 121 patients, the majority experienced mild or asymptomatic cases, with serious outcomes primarily linked to older age and specific comorbidities (like bronchiectasis and cardiopathy) rather than the type of IEI itself.
  • - Despite most infections being mild, the case fatality rate for these patients was higher than the general population, highlighting the need for targeted care in individuals with IEI.
View Article and Find Full Text PDF

In the last few years, new primary immunodeficiencies and genetic defects have been described. Recently, immunoglobulin products with improved compositions and for subcutaneous use have become available in Brazil. In order to guide physicians on the use of human immunoglobulin to treat primary immunodeficiencies, based on a narrative literature review and their professional experience, the members of the Primary Immunodeficiency Group of the Brazilian Society of Allergy and Immunology prepared an updated document of the 1st Brazilian Consensus, published in 2010.

View Article and Find Full Text PDF