Outcomes of a Structured Olfactory and Gustatory Rehabilitation Program in Children with Post-COVID-19 Smell and Taste Disturbances.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is closely related to SARS-CoV and uses angiotensin-converting enzyme 2 as its cellular receptor. In early 2020, reports emerged linking CoV disease 2019 (COVID-19) to olfactory and gustatory disturbances. These disturbances could be attributed to virus-induced damage to olfactory neurons or immune responses, thereby affecting sensory functions.

A comparative meta-analysis of mini-transverse versus longitudinal techniques in the treatment of carpal tunnel syndrome.

Background: Carpal tunnel syndrome (CTS) is a common nerve entrapment condition, and there is ongoing debate regarding the superiority of traditional open versus minimally invasive carpal tunnel surgery.

Methods: This meta-analysis reviewed six studies involving 478 patients to compare recovery and functional outcomes between the traditional longitudinal technique and the minimally invasive mini-transverse technique. The primary outcomes included the functional status scale (FSS), symptoms severity scale (SSS), pain scores, time to return to work, duration of operation, and incidence of complications.

Repurposing Dapagliflozin for Mitigation of the Kidney Injury Triggered by Cadmium in Rats: Role of Autophagy, Apoptosis, and the SIRT1/Nrf2/HO-1 Pathway.

The antioxidant/antiapoptotic features of dapagliflozin (DPG) have mediated its beneficial actions against several experimental models. However, no studies have been conducted to determine whether DPG mitigates the renal injury triggered by cadmium (Cd). Herein, DPG was studied for its potential to attenuate kidney damage in Cd-intoxicated rats, as well as to unravel the mechanisms involving oxidative events, autophagy, and apoptosis.

Effect of Laser Photobiomodulation on Postoperative Pain After Single-Visit Endodontic Treatment in Children: A Randomized Control Trial.

Background: This study aimed to assess the effectiveness of laser photobiomodulation (PBM) in reducing postoperative pain following single-visit endodontic treatment in children aged 5-9 years.

Methods: Forty children aged 5-9 years with acute irreversible pulpitis in deciduous molars requiring single-visit pulpectomy were included in the study. Pulpectomy was performed according to a standard endodontic protocol.

A combined therapy of meropenem-ZnO nanoparticles efficiently eliminates carbapenem-resistant Klebsiella pneumoniae biofilms, with reduced nephrotoxicity (in vitro).

In response to the World Health Organization's research agenda of antimicrobial resistance in human health, this study appraised the antibacterial and antibiofilm synergistic activity of meropenem and ZnO nanoparticles (ZnO-NPs) combination against carbapenem-resistant Klebsiella pneumoniae (CRKP). The minimum inhibitory concentration (MIC) of meropenem in combination was found to be ~1/12 of its MIC alone. The results of microtiter dilution assay showed that the combination was more efficient in reducing the biofilm biomass than meropenem alone or ZnO-NPs alone.

Strategies to Implement a Community-Based, Longitudinal Cohort Study: The Whole Communities-Whole Health Case Study.

This paper discusses the implementation of the Whole Communities-Whole Health (WCWH) initiative, which is a community-based, longitudinal cohort study. WCWH seeks to better understand the impact of location on family health and child development while also providing support for families participating in the study. Implementing a longitudinal study that is both comprehensive in the data it is collecting and inclusive in the population it is representing is what makes WCWH extremely challenging.

Understanding decision making for the use of atraumatic restorative approach based on non-clinical factors by Indian pedodontists - a conjoint analysis.

Background: Atraumatic Restorative Treatment (ART) approach is considered as one of the minimally invasive interventions. The success of restoration depends on various clinical factors like material, patient and operator factor. Conjoint analysis is a technique for measuring individual's preference structures via systematical variations of products attributes in an experimental design.

Incidence of pediatric traumatic brain injury (TBI) during the working hours of parents and caregivers in Saudi Arabia: A survey study.

Background: Traumatic brain injury (TBI) is a common result of external physical forces that damage the brain, affecting over 50 million people annually, with a higher prevalence in males. Children aged 0-4 years are the most susceptible, particularly in low-and middle-income countries, where 90% of TBI-related deaths occur. TBI significantly affects children's quality of life.

Evaluation of anti-acne activity of human whole saliva against acne vulgaris: An in vitro study.

Background: Acne vulgaris (AV) is a multifactorial inflammatory skin disorder, affecting 9.45% of the world's population. AV can be painful, discomforting, and disfiguring due to scarring, leading to physiological distress, and economic burden.

Brainstem Toxicity Following Proton Beam Radiation Therapy in Pediatric Brain Tumors: A Systematic Review and Meta-Analysis.

Proton beam radiation therapy (PBRT) is an advanced cancer treatment modality that utilizes the distinctive physical properties of protons to precisely deliver radiation to tumor targets while sparing healthy tissue. This cannot be obtained with photon radiation. In this systematic review and meta-analysis, we aimed to comprehensively assess the risk of brainstem toxicity in pediatric brain tumor patients undergoing PBRT.

Effects of probiotics on selected anthropometrics and biochemical measures in overweight or obese Saudi subjects: a double-blind, placebo-controlled, randomised clinical trial.

Objective: This study aimed to assess the effects of multi-strain probiotics on anthropometric and biochemical measures in Saudi adults with overweight or obesity.

Design: Single-centre, double-blind, placebo-controlled, randomised clinical trial.

Setting: Occupational Health Clinics at King Saud University Medical City, Riyadh, Saudi Arabia.

Examining the Association between Social Media Use and Dietary Habits among College Students in Riyadh, Saudi Arabia.

Food culture plays a vital role in societal dynamics, with various factors influencing dietary choices beyond hunger. Among these factors are external eating, triggered by environmental cues, and emotional eating, which are common stress-coping mechanisms among college students. Social media has a significant impact on nutrition by providing access to food-related content, which can lead to restrictive diets or unhealthy eating habits.

Does Tranexamic Acid Administration Increase the Risk of Thromboembolism?

Introduction Hemorrhage following trauma is one of the leading causes of death worldwide. Venous thromboembolism (VTE) is a common complication of an increased coagulable state, and the risk of VTE following the administration of tranexamic acid (TXA), an antifibrinolytic agent, is still controversial. Our aim is to understand whether there is any association between the administration of TXA and the risk of VTE development.

Association Between ABO Blood Group, Dental Caries, Gingivitis, Impacted Teeth and Malocclusion Among Saudi Adults: A Cross-Sectional Study.

Background: Whether there is a relationship between blood group and the likelihood of acquiring oral diseases. Therefore, the present study investigated the potential association between ABO blood groups and various dental conditions, including dental caries, gingivitis, malocclusion, and impacted teeth, in Saudi adults aged 18 years and older.

Methods: A cross-sectional study was conducted on 300 participants who met the inclusion criteria.

Assessment of Patient Satisfaction and Oral Health-Related Quality of Life Following Full Mouth Rehabilitation with Implant-Supported Prostheses.

Background: The concept of success is typically established by the researcher or the practitioner rather than the patient, who has the greatest stake in the outcome of the prosthodontics therapy.

Aim: To assess patient satisfaction and oral health-related quality of life (OHRQoL) in following full mouth rehabilitation with implant-supported prostheses (ISP).

Methods And Materials: Thirty-two patients who underwent full mouth rehabilitation with ISP were included in this study.

Clinical Evaluation of the Long-Term Survival and Success Rates of Different Types of Implant-Supported Prostheses.

Background: Dental implants have been essential to the therapy of patients who are partially edentulous.

Aim: Clinical evaluation of the long-term survival and success rates of different types of implant-supported prostheses.

Materials And Methods: Patients who had a healthy edentulous ridge of three missing teeth in the posterior jaw in which two or three dental implants were placed having any of three prostheses, namely, three-unit fixed dental prostheses (FPD) on two implants, three splinted crowns on three implants, and three splinted crowns on three implants were included.

Evaluation of Complications Associated with Fixed Partial Denture: A Prospective Study.

Objective: To assess complications, survival rates, and patient-reported outcomes associated with fixed partial dentures (FPDs).

Methods: A cohort of 146 subjects, aged 18 and above, requiring FPD were recruited. Following comprehensive dental examinations, FPDs were fabricated.

Exploring the Impact of Orthodontic Treatment on Temporomandibular Joint Health.

Background: Currently, one of the most prevalent oral abnormalities is malocclusion. There is a rising percentage of patients who are willing to undertake orthodontic procedures.

Aim: To evaluate the impact of orthodontic treatment on the morphology of temporomandibular joint (TMJ) in patients with malocclusion associated with TMJ abnormality such as skeletal class II deep bite malocclusion using CBCT.

Perceived Barriers of Clinical Roles Towards Intensive Care Unit Mobility.

There is overwhelming evidence of improved patient outcomes as a result of early mobilization in the intensive care unit (ICU). However, several barriers of ICU mobility remain understated with reference to clinical roles. The purpose of this study is to investigate the perceived barriers of early mobility of critically ill patients among ICU healthcare providers.

Effect of Hyaluronic Acid on Socket Healing After Lower Impacted Third Molar Tooth Extraction in 40 Dental Patients.

BACKGROUND Surgical extraction of impacted mandibular third molars is the most commonly performed procedure in oral surgery; its associated complications include sensory nerve damage, swelling, and trismus. This study aimed to evaluate the effects of hyaluronic acid (HA) on healing of the socket following extraction of the lower impacted third molar tooth in 40 dental patients. MATERIAL AND METHODS This prospective, double-blind, randomized, controlled study was carried out on 40 adult healthy patients indicated for surgical removal of bilateral impacted mandibular third molars with equal surgical difficulty (moderate surgical difficulty according to the Koerner index.