Publications by authors named "Alma L Ladron de Guevara Cetina"
N Engl J Med
February 2024
Article Synopsis
- Seladelpar, a medication aimed at treating primary biliary cholangitis, was tested in a phase 3 trial involving patients who didn't respond well to the standard treatment, ursodeoxycholic acid.
- The trial showed that a significantly higher percentage of patients taking seladelpar achieved a biochemical response and normalized alkaline phosphatase levels compared to those on placebo.
- Additionally, seladelpar was more effective in reducing itchiness, with patients reporting greater relief from pruritus than those receiving placebo, although some adverse events were noted.
