Publications by authors named "Alma Blazquez Martin"
Calcifying fibrous tumor (CFT) is a rare, benign, mesenchymal tumor. It has a slight female predominance, and it can appear in any range of age. It can be in the extremities, neck, and gastrointestinal tract, but it has also been described in other locations.
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- Colorectal cancer is a major health issue, being the fourth leading cause of cancer deaths, with rectal cancer contributing significantly to these statistics; recent studies show promising advancements in neoadjuvant therapies.
- * A study involving 181 patients with locally advanced rectal cancer examined the effects of neoadjuvant chemoradiotherapy on tumor regression and surgical outcomes, utilizing the Mandard grading system for analysis.
- * The findings indicated that greater tumor regression correlates with improved disease-free survival rates and reduced local recurrence and distant metastasis, highlighting the importance of tumor response to therapy on long-term disease progression.
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- * CRC primarily spreads to lymph nodes, liver, and lungs, while bone metastases are rare and usually appear alongside other metastases, significantly impacting patient quality of life and prognosis.
- * The study details a case of a patient who had successful surgery for stage IV rectal adenocarcinoma but developed a rare costal wall metastasis 79 months later, highlighting the need for personalized patient management.
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- Spontaneous cervical hematoma often arises from bleeding in or around the parathyroid gland, typically linked to conditions like giant adenomas or hyperplasia, and can lead to severe complications if it compresses the airway.
- For stable patients, treatment generally includes monitoring and possible delayed surgery, while those with airway issues require urgent surgical intervention.
- The case study discusses a 78-year-old patient with multiple health issues who experienced neck pain and respiratory problems due to a spontaneous cervical hematoma from a giant parathyroid adenoma, resulting in complicated post-operative recovery.
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- Adipocytic tumors are the most common soft tissue cancers, with liposarcoma being the most prevalent malignant type; however, their evolution and prognosis, especially in retroperitoneal areas, haven't been well studied before.
- A retrospective analysis was conducted on 52 patients diagnosed with liposarcoma from 2000 to 2020, categorizing them based on tumor location (retroperitoneal vs. non-retroperitoneal) and examining factors like recurrence, treatment, and mortality.
- The study found significant differences in survival rates of liposarcoma subtypes based on their location, with better outcomes for certain types in non-retroperitoneal regions; surgical margins were crucial for prognosis,
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- - The study analyzed survival factors in patients with peritoneal metastasis (PM) from colorectal cancer (CRC), focusing on whether PM was detected simultaneously with the primary tumor or developed later.
- - Out of 1882 colorectal cancer patients treated, 240 (12.8%) were included, revealing that certain factors like KRAS mutation and peritoneal carcinomatosis index (PCI) significantly influenced survival rates, with better outcomes for patients with lower PCI scores.
- - The findings emphasized that PCI remains a critical prognostic indicator, with specific survival rates highlighted based on the categorization of patients by PCI scores and other tumor characteristics.
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- Pancreatic necrosis infection (PNI) occurs in 20-40% of severe acute pancreatitis cases, often caused by anaerobic bacteria like Clostridium.
- A 60-year-old patient with a history of SARS-CoV-2 developed PNI, leading to pancreatic gas gangrene detected by CT scan, resulting in surgical necrosectomy.
- After surgery and medical treatment, the patient's condition improved, and he was discharged 76 days later; however, there’s a consensus that infections like these require more aggressive treatment due to their high mortality risk.
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- - The study focused on identifying survival predictors for stage IV colorectal cancer patients with liver metastases, using data from 104 patients diagnosed between 2013 and 2018.
- - Key findings revealed that patients with wild-type KRAS tumors had a significantly higher survival rate (42%) compared to those with mutated KRAS tumors (9%).
- - Variables like KRAS mutation, tumor stage, and treatment approaches showed independent predictive value for survival, but the type of initial treatment (chemotherapy vs. tumor resection) did not significantly affect survival outcomes.