Publications by authors named "Allyson Roe"

Synopsis of recent research by authors named "Allyson Roe"

  • - Allyson Roe's research primarily focuses on the interactions between amyloid-beta and tau proteins in the context of Alzheimer's disease, exploring how these proteins contribute to neurodegeneration and cognitive decline through various mechanisms.
  • - Her studies emphasize the complex role of apolipoprotein E (APOE) in neuroprotection and neurotoxicity, revealing how different APOE isoforms affect amyloid-beta deposition and synaptic integrity, particularly in aging and Alzheimer's models.
  • - Roe's work also investigates the role of microglia in tau pathology and the potential therapeutic strategies targeting tau reduction as a means to prevent neuronal death and pathological progression in tauopathies.

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