Publications by authors named "Allyson Gross"
Article Synopsis
- - This study examines how exposure to alcohol and cannabis (specifically THC) during pregnancy affects certain types of inhibitory interneurons in the hippocampus of rats, focusing on somatostatin and neuropeptide Y (NPY) neurons.
- - Pregnant rats were exposed to either alcohol or air and THC or a placebo, with the effects on interneuron densities analyzed after birth, revealing sex-specific changes in neuron populations.
- - The findings suggest that both THC and alcohol can impact brain function developmentally, particularly by altering inhibition processes in a way that varies between male and female rats.
Mild traumatic brain injuries (mTBIs) are a prevalent health issue in North America. There is increasing pressure to utilize ecologically valid models of closed-head mTBI in the preclinical setting to increase translatability to the clinical population. The awake closed-headed injury (ACHI) model uses a modified controlled cortical impactor to deliver closed-headed injury, inducing clinically relevant behavioral deficits without the need for a craniotomy or the use of an anesthetic.
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