Credibility of a meta-analysis: evidence-based practice concerning soy intake and breast cancer risk in premenopausal women.

Purpose: To report the findings from a critical appraisal concerning the credibility of a meta-analysis (M-A) about the role of dietary soy intake in reducing breast cancer risk. The use of an evidence-based, advanced nursing practice framework was used to appraise the M-A.

Approach: The clinical question was developed from a problem that could be encountered in clinical practice.

Exposure of brain to high-dose, focused gamma rays irradiation produces increase in leukocytes-adhesion and pavementing in small intracerebral blood vessels.

Objective: Radiosurgery is used to destroy a predetermined target within the brain, with minimal radiation injury to the surrounding tissue. We hereby present our in vivo model to study the effects of single-session, high-dose radiation on the cerebral vessels that are targeted with radiosurgery using the Leksell Gamma Knife.

Methods: The study was conducted in 29 adult male WT C57BL/6J mice weighing 21 to 28 g (6-8 wk old).

Primary central nervous system lymphoma of the brain stem responding favorably to radiosurgery: a case report and literature review.

Objective: To explore various therapeutic alternatives and evaluate the clinical results of patients with primary central nervous system lymphoma (PCNSL). We report a case of PCNSL with involvement of the brain stem managed with radiosurgery using the Leksell gamma knife as the treatment modality.

Case Description: A 55-year-old white woman presented with complaints of weakness on the left side of her body and double vision associated with a frontal headache.

Assessment of pain control, quality of life, and predictors of success after gamma knife surgery for the treatment of trigeminal neuralgia.

Object: There are various surgical treatment alternatives for trigeminal neuralgia (TN), but there is no single scale that can be used uniformly to assess and compare one type of intervention with the others. In this study the objectives were to determine factors associated with pain control, pain-free survival, residual pain, and recurrence after gamma knife surgery (GKS) treatment for TN, and to correlate the patients' self-reported quality of life (QOL) and satisfaction with the aforementioned factors.

Methods: Between the years 2000 and 2004, the authors treated 81 patients with medically refractory TN by using GKS.

First 100 cases of gamma knife radiosurgery in Louisiana: analysis of demographics and early results.

Louisiana's first ever Leksell Gamma Knife was commissioned at Louisiana State University Health Sciences Center (LSUHSC) in Shreveport in January 2000. Between January 2000 and January 2001,113 patients with various indications were treated using the 201-source Co-60 Leksell model "B" Gamma Knife (Elekta Instruments, Atlanta, Georgia) at LSUHSC-Shreveport. Sixty-three patients were female and 50 were male.