Publications by authors named "Allyson Cundiff"
Article Synopsis
- Oxytocin (OT) is a crucial neuropeptide linked to social behavior and motivation, and its effectiveness in treating autism spectrum disorder (ASD) has shown mixed results.
- A study examined the relationship between genetic and epigenetic factors and OT levels in 290 ASD participants involved in an OT clinical trial.
- The researchers found new genetic connections to OT levels, linked to known ASD risk genes, and significant associations between OT levels and genetic expression or epigenetic changes, potentially aiding future research on ASD and OT therapy.
Article Synopsis
- Pediatric behavioral health admissions are increasing, and the study aimed to reduce the use of physical restraints from an initial 2.6% of patient days to below 1% to ensure safer care for children exhibiting violent behaviors.* -
- A multidisciplinary team implemented targeted interventions from July 2018 to February 2020, leading to a decrease in physical restraint orders to 0.9% over 19 months without increasing staff injuries.* -
- The findings demonstrate that with team-based quality improvement strategies, children's hospitals can effectively reduce reliance on physical restraints in the treatment of behavioral health conditions.*
Medical Etiologies of Secondary Psychosis in Children and Adolescents.
Child Adolesc Psychiatr Clin N Am
January 2020
This is an updated review of child and adolescent somatic disorders associated with psychosis/psychotic symptoms, organized into neurologic, infectious, genetic, inborn errors of metabolism, autoimmune, rheumatologic, endocrine, nutritional, metabolic, and iatrogenic categories. When possible clinical manifestations or types of psychotic symptoms and proposed neuropathogenesis causing the neuropsychiatric symptoms are included. In some cases, the psychiatric symptoms may be the first presentation of the disease.
View Article and Find Full Text PDFAnti-N-Methyl d-Aspartate Receptor Encephalitis and Electroconvulsive Therapy: Literature Review and Future Directions.
Child Adolesc Psychiatr Clin N Am
January 2019
Despite the majority of patients with anti-N-methyl d-aspartate receptor (NMDAR) antibody encephalitis presenting with catatonic symptoms, the literature has not focused on well-known treatments for catatonia, such as electroconvulsive therapy (ECT). The authors review the literature identifying case reports that document the effective use of ECT for anti-NMDAR encephalitis. They also identify gaps in the literature regarding use and documentation of ECT and review possible mechanisms of action for ECT.
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