Dereplication of extract with anti-inflammatory activity.

is a medicinal plant widely used by indigenous communities of the Amazon rainforest to treat inflammatory diseases and related pathologies. Considering its ethnopharmacological application, it constitutes an important source of biologically active molecules in the development of anti-inflammatory drugs. This study describes a dereplication methodology of the bioactive extract from leaves and the evaluation of the anti-inflammatory potential in an inflammatory model with mice of the BALB/c lineage and using cell lines, as well as determining the production of an inflammatory mediator.