Host-Induced Gene Silencing of a Using Bean Pod Mottle Virus as a Vehicle Reduces Disease on Soybean.

A lack of complete resistance in the current germplasm complicates the management of Sclerotinia stem rot (SSR) caused by in soybean. In this study, we used bean pod mottle virus (BPMV) as a vehicle to down-regulate expression of a key enzyme in the production of an important virulence factor in , oxalic acid (OA). Specifically, we targeted a gene encoding oxaloacetate acetylhydrolase (), because deletion mutants are OA deficient and non-pathogenic on soybean.