Publications by authors named "Allison Rhee"
Article Synopsis
- The study aimed to explore the effectiveness of McConnell's sign in predicting normotensive shock in patients with intermediate-risk pulmonary embolism (PE).
- Researchers analyzed patients who received percutaneous mechanical thrombectomy and defined normotensive shock based on specific blood pressure and cardiac output metrics.
- Results showed that McConnell's sign was associated with higher instances of normotensive shock and other indicators of poor outcomes, suggesting it could be a valuable predictive tool, though further research is needed to confirm these findings.
Article Synopsis
- Common SNPs may account for 40-50% of human height variation, and this study identifies 12,111 SNPs linked to height from a large sample of 5.4 million individuals.
- These SNPs cluster in 7,209 genomic segments, encompassing about 21% of the genome and showing varying densities enriched in relevant genes.
- While these SNPs explain a substantial portion of height variance in European populations (40-45%), their predictive power is lower (10-24%) in other ancestries, suggesting a need for more research to enhance understanding in diverse populations.
We had proposed earlier that the anaerobe Oxalobacter formigenes sustains a proton-motive force by exploiting a secondary carrier rather than a primary proton pump. In this view, a carrier protein would catalyze the exchange of extracellular oxalate, a divalent anion, and intracellular formate, the monovalent product of oxalate decarboxylation. Such an electrogenic exchange develops an internally negative membrane potential, and since the decarboxylation reaction consumes an internal proton, the combined activity of the carrier and the soluble decarboxylase would constitute an "indirect" proton pump with a stoichiometry of 1H+ per turnover.
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