Publications by authors named "Allison Pearce"
Objective: Visualizing implanted subdural electrodes in three-dimensional (3D) space can greatly aid in planning, executing, and validating resection in epilepsy surgery. Coregistration software is available, but cost, complexity, insufficient accuracy, or validation limit adoption. We present a fully automated open-source application, based on a novel method using postimplant computerized tomography (CT) and postimplant magnetic resonance (MR) images, for accurately visualizing intracranial electrodes in 3D space.
View Article and Find Full Text PDFArticle Synopsis
- High-frequency oscillations (HFOs), categorized as ripples (100-250 Hz) or fast ripples (250-500 Hz), serve as potential biomarkers for identifying seizure-prone brain areas in patients with epilepsy.
- Researchers analyzed HFO data from five epilepsy patients using an automated algorithm, focusing on changes in HFO characteristics across different seizure-related time periods (interictal, preictal, ictal, and postictal).
- The study found significant, patient-specific fluctuations in HFO morphology and rates, indicating the potential for these temporal changes to inform customized seizure prediction methods and enhance understanding of seizure mechanisms.