Publications by authors named "Allison P Anderson"

Exploration beyond low Earth orbit requires innovative solutions to support the crew medically, especially as the opportunity for timely evacuation to Earth diminishes. This includes assessing the risks and benefits that a complicated medical evacuation (MEDEVAC) poses to the injured crewmember, the crew, and the mission. This qualitative study identifies common MEDEVAC risk assessment principles used in spaceflight and other extreme environments to better inform future risk assessment tools and exploration mission concepts.

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Adding noise to a system to improve a weak signal's detectability is known as stochastic resonance (SR). SR has been shown to improve sensory perception and cognitive performance in certain individuals, but it is unknown whether this performance improvement can translate to meaningful macrocognitive enhancements in performance for complex, operational tasks. We investigated human operator performance in a lunar landing simulation while applying auditory white noise and/or noisy galvanic vestibular stimulation.

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Background: The uncertain environments of future space missions means that astronauts will need to acquire new skills rapidly; thus, a non-invasive method to enhance learning of complex tasks is desirable. Stochastic resonance (SR) is a phenomenon where adding noise improves the throughput of a weak signal. SR has been shown to improve perception and cognitive performance in certain individuals.

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Background: Adding noise to a system to improve a weak signal's throughput is known as stochastic resonance (SR). SR has been shown to improve sensory perception. Some limited research shows noise can also improve higher order processing, such as working memory, but it is unknown whether SR can broadly improve cognition.

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Surface extravehicular activity (sEVA) will be a critical component of future human missions to the Moon. sEVA presents novel risks to astronaut crews not associated with microgravity operations due to fundamental differences in task demands, physiology, environment, and operations of working on the lunar surface. Multimodal spacesuit informatics displays have been proposed as a method of mitigating sEVA risk by increasing operator autonomy.

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An electrocardiograph records the periodic voltage generated by the heart over time. There is growing demand to continuously monitor the ECG for proactive health care and human performance optimization. To meet this demand, new conductive textile electrodes are being developed which offer an attractive alternative to adhesive gel electrodes but they come with their own challenges.

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Objective: We use a set of unobtrusive measures to estimate subjectively reported trust, mental workload, and situation awareness (henceforth "TWSA").

Background: Subjective questionnaires are commonly used to assess human cognitive states. However, they are obtrusive and usually impractical to administer during operations.

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The detection of psychological stress using the electrocardiogram (ECG) signal is most commonly based on the detection of the R peak-the most prominent part of the ECG waveform-and the heart rate variability (HRV) measurements derived from it. For stress detection algorithms focused on short-duration time windows, there is potential benefit in including HRV features derived from the detection of smaller peaks within the ECG waveform: the P, Q, S, and T waves. However, the potential drawback of using these small peaks is their smaller magnitude and subsequent susceptibility to noise, making them more difficult to reliably detect.

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Heel-lift is a subjectively reported fit issue in planetary spacesuit boot prototypes that has not yet been quantified. Inertial measurement units (IMUs) could quantify heel-lift but are susceptible to integration drift. This work evaluates the use of IMUs and drift-correction algorithms, such as zero-velocity (ZVUs) and zero-position updates (ZPUs), to quantify heel-lift during spacesuited gait.

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Objective: Microbial dysbiosis, a shift from commensal to pathogenic microbiota, is often associated with mental health and the gut-brain axis, where dysbiosis in the gut may be linked to dysfunction in the brain. Many studies focus on dysbiosis induced by clinical events or traumatic incidents; however, many professions in austere or demanding environments may encounter continuously compounded stressors. This study seeks to explore the relationship between microbial populations and stress, both perceived and biochemical.

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Background: Astronauts live and work in isolated, confined, extreme (ICE) environments that create both high stress and the need for high performance. The COVID-19 pandemic created ICE-like conditions across the globe by confining people to their homes under the ever-present threat of disease. Our goal is to understand the impact of prior experience in ICE on coping, using the pandemic as a pseudo space analog environment.

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Background: Stochastic resonance (SR) is achieved when a faint signal is improved with the addition of the appropriate amount of white noise. Perceptual thresholds are expected to follow a characteristic performance improvement curve as a function of the white noise level added (i.e.

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Wearable physiological monitoring systems are becoming increasingly prevalent in the push toward autonomous health monitoring and offer new modalities for playful and purposeful interaction within human computer interaction (HCI). Sensing systems that can be integrated into garments and, therefore, daily activities offer promising pathways toward ubiquitous integration. The electrocardiogram (ECG) signal is commonly monitored in healthcare and is increasingly utilized as a method of determining emotional and psychological state; however, the complete ECG waveform with the P, Q, R, S, and T peaks is not commonly used, due to the challenges associated with collecting the full waveform with wearable systems.

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Alternative reality (XR) technologies, including physical, augmented, hybrid, and virtual reality, offer ways for engineered spaces to be evaluated. Traditionally, practitioners (such as those designing spacecraft habitats) have relied on physical mockups to perform such design evaluations, but digital XR technologies present several streamlining advantages over their physical counterparts. These digital environments vary in their level of virtuality, and consequently have different effects on human perception and performance, with respect to a completely physical mockup environment.

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A detailed understanding of foot morphology can enable the design of more comfortable and better fitting footwear. However, foot morphology varies widely within the population, and changes dynamically as the foot is loaded during stance. This study presents a parametric statistical shape model from 4D foot scans to capture both the inter- and intra-individual variability in foot morphology.

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Internal jugular flow is reduced in space compared with supine values, which can be associated with internal jugular vein (IJV) thrombosis. The mechanism is unknown but important to understand to prevent potentially serious vein thromboses on long duration flights. We used a novel, microgravity-focused numerical model of the cranial vascular circulation to develop hypotheses for the reduced flow.

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Background: Stochastic resonance (SR) refers to a faint signal being enhanced with the addition of white noise. Previous studies have found that vestibular perceptual thresholds are lowered with noisy galvanic vestibular stimulation (i.e.

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Electrical signals produced within the human body can reveal information about a wide variety of physiological processes including physical activity, cardiac health, and psychological state. The industry standard for physiological signal detection is the use of adhesive electrodes that stick onto the skin. These electrodes can irritate the skin over long periods of time and are not reusable, making them a challenge for use in operational environments.

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Wearable health-monitoring systems should be comfortable, non-stigmatizing, and able to achieve high data quality. Smart textiles with electronic elements integrated directly into fabrics offer a way to embed sensors into clothing seamlessly to serve these purposes. In this work, we demonstrate the feasibility of electrocardiogram (ECG) monitoring with sewn textile electrodes instead of traditional gel electrodes in a 3-lead, chest-mounted configuration.

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Introduction: We evaluated the reproducibility of two portable, self-administered autorefractors (Netra and SVOne Pro) to assess the time course of visual changes on the ISS.

Methods: We measured cycloplegic refractive error at 5 visits at least a week apart in 13 subjects (6 women, 7 men, 30 ± 9 yr) using both devices seated and also prone with lower body positive pressure (LBPP) applied. Axial length was measured with an optical biometer.

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On Earth, tissue weight generates compressive forces that press on body structures and act on the walls of vessels throughout the body. In microgravity, tissues no longer have weight, and tissue compressive forces are lost, suggesting that individuals who weigh more may show greater effects from microgravity exposure. One unique effect of long-duration microgravity exposure is spaceflight-associated neuroocular syndrome (SANS), which can present with globe flattening, choroidal folds, optic disk edema, and a hyperopic visual shift.

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Artificial gravity (AG) has been proposed as a countermeasure to spaceflight-associated neuro-ocular syndrome (SANS). The etiology of SANS is unknown but mimicking gravitational loading through AG may mitigate these negative adaptations. Seventeen subjects (nine men, eight women; 18-32 yr) were analyzed in four experimental conditions: 1) standing, 2) supine, 3) AG with the center of rotation at the eye (AGEC), and 4) AG with 2 Gs at the feet (AG2G).

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Some astronauts are returning from long-duration spaceflight with structural ocular and visual changes. We investigated both the transient and sustained effects of changes in the direction of the gravity vector acting on the eye using changes in body posture. Intraocular pressure (IOP; measured by Perkins tonometer), ocular geometry (axial length, corneal thickness, and aqueous depth-noncontact biometer), and the choroid (volume and subfoveal thickness optical coherence tomography) were measured in 10 subjects (5 males and 5 females).

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Introduction: Virtual reality (VR) can provide exposure to nature for those living in isolated confined environments. We evaluated VR-presented natural settings for reducing stress and improving mood.

Methods: There were 18 participants (9 men, 9 women), ages 32 ± 12 yr, who viewed three 15-min 360° scenes (an indoor control, rural Ireland, and remote beaches).

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