Publications by authors named "Allison Oliva"
Notable Programs in Neurotology Series: The University of Miami Ear Institute.
Otol Neurotol Open
December 2024
The University of Miami Ear Institute (UMEI) was conceived and founded by Dr. W. Jarrard (Jerry) Goodwin in 1990, then Chairman of the University of Miami Department of Otolaryngology-Head and Neck Surgery.
View Article and Find Full Text PDFObjective: A publicly available large language learning model platform may help determine current readability levels of otolaryngology patient education materials, as well as translate these materials to the recommended 6th-grade and 8th-grade reading levels.
Study Design: Cross-sectional analysis.
Setting: Online using large language learning model, ChatGPT.
Purpose: The purpose of this study was to evaluate the association between self-reported hearing handicap and life-space mobility utilizing the Life-Space Questionnaire (LSQ). Life-space mobility reflects how an individual moves through their daily physical and social environment, and the role of hearing loss in life-space mobility is not fully understood. We hypothesized that those with higher self-reported hearing handicap would be more likely to demonstrate restricted life-space mobility.
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- * In a study of olfactory tissue from patients with long-lasting smell loss, researchers found a persistent inflammatory response characterized by T cell infiltration and changes in myeloid cell populations.
- * The findings suggest that even after the virus is cleared, inflammation in the olfactory epithelium may cause ongoing dysfunction of smell receptors, potentially explaining why some patients continue to struggle with olfactory issues post-COVID-19.
Most human subjects infected by SARS-CoV-2 report an acute alteration in their sense of smell, and more than 25% of COVID patients report lasting olfactory dysfunction. While animal studies and human autopsy tissues have suggested mechanisms underlying acute loss of smell, the pathophysiology that underlies persistent smell loss remains unclear. Here we combine objective measurements of smell loss in patients suffering from post-acute sequelae of SARS-CoV-2 infection (PASC) with single cell sequencing and histology of the olfactory epithelium (OE).
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- Presbyosmia, or age-related loss of smell, impacts many individuals over 65 and is linked to damage in the olfactory epithelium, though its mechanisms remain unclear and lack treatment options.
- The study utilized various methods, including biopsies and single-cell RNA sequencing, to investigate cellular changes in the olfactory epithelium of older adults, revealing inflammation-related alterations in stem cells that affect their ability to function properly.
- Findings suggest that these inflammatory changes in olfactory epithelium stem cells could be a key factor in the development of presbyosmia, indicating they may serve as a potential target for therapeutic interventions to restore sense of smell.
Purpose: The purpose of this study was to determine the test-retest reliability and the minimum detectable change (MDC) scores of the Listening Self-Efficacy Questionnaire (LSEQ).
Method: A total of 77 older adults who were experienced hearing aid users were administered the LSEQ in pen-paper format on two separate occasions. They were provided the first copy of the LSEQ in the clinic to take home to complete.