Publications by authors named "Allison Mandich"
Article Synopsis
- The All of Us Research Program faced significant disruptions due to the COVID-19 pandemic, forcing a pause on in-person interactions for participant data collection.
- Prior to the pandemic, the program was enrolling about 12,500 participants monthly across over 400 sites, but had to shift to new methods to maintain data collection remotely.
- As of February 2022, 224 clinical sites resumed in-person activities with enhanced safety measures, while all partners have implemented remote data collection methods to minimize risk.
Starting with the launch of the Human Genome Project three decades ago, and continuing after its completion in 2003, genomics has progressively come to have a central and catalytic role in basic and translational research. In addition, studies increasingly demonstrate how genomic information can be effectively used in clinical care. In the future, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into almost all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics for everyday life.
View Article and Find Full Text PDFSince its start, the Mammalian Gene Collection (MGC) has sought to provide at least one full-protein-coding sequence cDNA clone for every human and mouse gene with a RefSeq transcript, and at least 6200 rat genes. The MGC cloning effort initially relied on random expressed sequence tag screening of cDNA libraries. Here, we summarize our recent progress using directed RT-PCR cloning and DNA synthesis.
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