Quantifying the Subharmonic Mucosal Wave in Excised Larynges via Digital Kymography.

Objectives: In this paper, a nonlinear least squares fitting method was proposed to quantify subharmonic mucosal waves.

Study Design And Methods: Subharmonic mucosal waves from 10 excised canine larynges were recorded using digital kymography and analyzed using nonlinear least squares and linear least squares methods. Amplitudes of fundamental and subharmonic mucosal wave components of right-upper, right-lower, left-upper, and left-lower vocal fold lips were calculated.

Quantitative Study for the Surface Dehydration of Vocal Folds Based on High-Speed Imaging.

Objectives: From the perspective of the glottal area and mucosal wave, quantitatively estimate the differences of vocal fold on laryngeal activity during phonation at three different dehydration levels.

Study Design: Controlled three sets of tests.

Methods: A dehydration experiment for 10 excised canine larynges was conducted at 16 cm H2O.

Functional and Histological Evaluation following Canine Vocal Fold Reconstruction Using Composite Thyroid Ala Perichondrium Flaps.

Objectives/hypotheses: We evaluated the effects of vocal fold reconstruction using a composite thyroid ala perichondrium flap (CTAP) after unilateral vocal fold stripping in beagles. We hypothesized that CTAP would improve glottic closure, decrease phonation threshold pressure, and decrease perturbation. In addition, vocal folds with CTAP would exhibit neovascularization and fat with increased von Willebrand factor (vWF) and smooth muscle actin (SMA), reflecting neoangiogenesis and flap viability.

Aerodynamic measures of glottal function: what extra can they tell us and how do they guide management?

Purpose Of Review: This article will define the major advances in laryngeal aerodynamics research from recent evidence-based literature.

Recent Findings: Recently published research focuses on new applications of aerodynamic parameters to improve patient diagnosis and outcomes, as well as further elucidating the mechanisms of phonation using computational modeling and excised larynges.

Summary: Although there is an extensive amount of research on improving the diagnosis and treatment of voice disorders using aerodynamics, the majority of recent literature lacks any conclusive evidence on new methods for use in the clinic; further research in these is needed.

Use of the rabbit larynx in an excised larynx setup.

Objective: To modify the excised larynx bench apparatus to accommodate experiments with rabbit larynges.

Study Design: Methodological study using ex vivo rabbit larynges.

Methods: Rabbit larynges (n=5) were dissected and mounted on a custom-made phonatory apparatus.