Patient-Prosthesis Mismatch in Pregnancy: A Multidisciplinary Approach.

A 24-year-old gravida 3 para 1 woman with history of bioprosthetic aortic valve replacement complicated by patient-prosthesis mismatch presented for prenatal care. Her pregnancy was managed by a multidisciplinary cardio-obstetrics team, resulting in an uncomplicated repeat cesarean section at term.

Strongyloides stercoralis Hyperinfection Syndrome in Pregnancy.

Strongyloidiasis is a parasitic infection with a high global burden of disease. Hyperinfection syndrome is a life-threatening complication that predominantly affects immunosuppressed individuals, such as those receiving corticosteroid treatment. Despite its worldwide prevalence, little is known about the clinical effects of this condition on the feto-maternal dyad during pregnancy.

Immunohistochemical detection of MUC5AC and MUC5B mucins in ferrets.

Objective: Cystic fibrosis (CF) is a genetic condition that causes abnormal mucus secretions in affected organs. MUC5AC and MUC5B are gel-forming mucins and frequent targets for investigations in CF tissues. Our objective was to qualify MUC5AC and MUC5B immunohistochemical techniques to provide a useful tool to identify, localize and interpret mucin expression in ferret tissues.

Oocyte Retrieval in Asymptomatic Patients Positive for SARS-CoV-2.

Objective: To report two cases of oocyte retrieval performed in asymptomatic SARS-CoV-2-positive patients.

Design: Case report. .

Utility of CD138/syndecan-1 immunohistochemistry for localization of plasmacytes is tissue-dependent in B6 mice.

Objective: Inflammation is present in many diseases and identification of immune cell infiltration is a common assessment. CD138 (syndecan-1) is a recommended immunohistochemical marker for human plasmacytes although it is also expressed in various epithelia and tumors. Similarly, CD138 is a marker for murine plasmacytes, but its tissue immunostaining is not well-defined.

Updates and Advances in the Management of Lateral Meniscal Radial Tears: A Critical Analysis Review.

Because of their increased mobility, lack of resistance to hoop stresses, and decreased blood supply, radial tears of the lateral meniscus are more troublesome to heal than vertical longitudinal tears. Given the success of meniscal root repairs, radial tears of the lateral meniscal body should be given strong consideration for repair because of a more reproducible ability to heal such lesions in young, active patients. Technique options that should be considered for the less common anterior radial tears of the lateral meniscus include outside-in repair, self-capturing suture-passing devices, and orthobiologic treatments to stimulate healing.

COVID-19 Implications on Clinical Clerkships and the Residency Application Process for Medical Students.

The coronavirus disease 2019 (COVID-19) pandemic has caused significant disruption to undergraduate medical education (UME). Although the immediate scheduling challenges are being addressed, there has been less discourse regarding how this pandemic will impact medical students in their preparation for and application to residency programs. While some historical disasters and pandemics provide a loose precedent for UME response during COVID-19, the impact of the current pandemic has surpassed any other events.

Anal sphincter botulinum toxin injection in children with functional anorectal and colonic disorders: A large institutional study and review of the literature focusing on complications.

Background And Aim: Botulinum toxin (botox) is a commonly used treatment for functional anorectal and colonic disorders. Although generally regarded as safe, complications associated with botox injection into the anal sphincters in children with severe defecation disorders are not well described. We aimed to review our institutional experience and the existing literature to better understand the safety of this practice.

Special care for persons with Alzheimer's disease and related dementias in Virginia adult care residences.

Designing supportive care for persons with Alzheimer's disease and related dementias in residential care is one of the most challenging issues facing researchers, policymakers, and facility administrators. To gain a better knowledge of the types of special care offered by adult care residences (ACRs) and assisted living facilities, the results of a survey of all licensed ACRs in the state of Virginia are presented. Examined are the facilities with special care units (SCUs) and special programs (SPs), the organizational characteristics of facilities that offer special care, the characteristics of existing SCUs and SPs, and the opinions of owners/operators on the elements needed for establishing these units and programs.