Production of random DNA oligomers for scalable DNA computing.

While remarkably complex networks of connected DNA molecules can form from a relatively small number of distinct oligomer strands, a large computational space created by DNA reactions would ultimately require the use of many distinct DNA strands. The automatic synthesis of this many distinct strands is economically prohibitive. We present here a new approach to producing distinct DNA oligomers based on the polymerase chain reaction (PCR) amplification of a few random template sequences.

Weak-localization-like temperature-dependent conductivity of a dilute two-dimensional hole gas in a parallel magnetic field.

We have studied the magnetotransport properties of a high mobility two-dimensional hole gas (2DHG) in a 10 nm GaAs quantum well with densities in the range of (0.7-1.6) x 10(10) cm(-2) on the metallic side of the zero-field "metal-insulator transition.

Two-dimensional metal in a parallel magnetic field.

We have investigated the effect of an in-plane parallel magnetic field (B(axially) on two high mobility metallic-like dilute two-dimensional hole gas systems in GaAs quantum wells. The experiments reveal that, while suppressing the magnitude of the low temperature resistance drop, B(axially) does not affect E(a), the characteristic energy scale of the metallic resistance drop. The field B(c) at which the metallic-like resistance drop vanishes is dependent on both the width of the quantum well and the orientation of B(axially).

Gene expression profiling diagnosis through DNA molecular computation.

Gene expression profiling is the characterization of cells based on the level of gene activity represented by concentrations of complementary DNA reverse transcribed from messenger RNA. The spectrum of cDNA concentrations, the expression profile, is determined using a DNA microarray. Although this approach is valuable for research, a simpler scheme that would give answers on a shorter time-scale for clinical applications is needed.