Publications by authors named "Allen Olha"

Article Synopsis
  • - Maternal obstructive sleep apnea-hypopnea (OSAH) is linked to pregnancy-related high blood pressure, and the study aimed to evaluate how well women with this condition could be recruited for a trial and adhere to positive airway pressure (PAP) treatment.
  • - Out of 105 women screened, 48 met the criteria for OSAH and were split into two groups: one received PAP therapy and the other used nasal dilator strips as a control, with adherence monitored and multiple health outcomes assessed.
  • - Results showed that both groups faced challenges in completion due to urgent deliveries or tolerability issues, but overall blood pressure control was achieved, with no significant differences in health outcomes between the two treatment groups. *
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Maternal obstructive sleep apnea-hypopnea (OSAH) is associated with hypertensive disorders of pregnancy (HDP). Attenuation of the normal nocturnal blood pressure (BP) decline (non-dipping) is associated with adverse pregnancy outcomes. OSAH is associated with nocturnal non-dipping in the general population, but this has not been studied in pregnancy.

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Background: Women with hyperglycemia during pregnancy are at high risk for adverse perinatal outcomes. Maternal sleep-disordered breathing (SDB) during pregnancy is common and is a risk factor for gestational diabetes mellitus (GDM). However, the relationship between SDB severity and glucose control is unknown.

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Gestational diabetes (GDM) is associated with adverse short- and long-term maternal and fetal outcomes. Observational data support a link between sleep-disordered breathing (SDB) during pregnancy and GDM. However, it is unknown whether treatment of SDB with continuous positive airway pressure (CPAP) improves glucose control in this patient population.

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Objective: It is unclear whether objectively measured maternal sleep-disordered breathing (SDB) leads to poor fetal outcomes. In this study, we prospectively assessed whether polysomnography-based diagnosis of SDB in the third trimester is associated with the delivery of small for gestational age (SGA) infants.

Study Design: Participants were recruited from a multicentre pregnancy cohort study.

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Background: Previous studies have suggested a link between obstructive sleep apnea and poor asthma control, which may be mediated through airway inflammation, obesity, and other mechanisms.

Objective: To test the hypothesis that the prevalence and severity of sleep apnea is greater among patients with severe compared with moderate asthma and controls without asthma.

Methods: Complete overnight home polysomnography was performed in 26 patients with severe asthma consecutively recruited to a difficult asthma program, 26 patients with moderate asthma, and 26 controls without asthma of similar age and body mass index.

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