Noncontact remineralization of incipient lesions treated with a 5% sodium fluoride varnish in vitro.

Purpose: Fluoride varnishes are appealing topical fluoride preparations that may provide anticaries benefits. The purpose of this in vitro study was to assess the noncontact remineralization effects of a commercial 5% sodium fluoride varnish on white spot lesions (WSLs).

Methods: Three-millimeter diameter enamel cores were extracted from bovine teeth, mounted in acrylic rods, ground and polished, and initially demineralized to create WSLs.

Remineralization of eroded enamel lesions by simulated saliva in vitro.

Purpose: The purpose of this study was to evaluate the effects of two simulated saliva (SS) remineralization solutions comprising different calcium-inorganic phosphate (Ca/P(i)) ratios on eroded enamel.

Methods: 3 mm diameter enamel cores were extracted from bovine teeth, mounted in acrylic rods, ground and polished,and initially demineralized with either 0.3% (120 minutes) or 1.

Effects on dentin treated with eluted multi-mineral varnish in vitro.

Purpose: The purpose of this pilot study was to assess the non-contact effects of a NaF varnish on the morphology and elemental compositions of sound and demineralized dentin in an in vitro pH cycling model.

Methods: 3 mm diameter dentin cores were extracted from bovine teeth, mounted in acrylic rods, and ground and polished. Sound and demineralized (in 10 mL unstirred 50% citric acid (pH = 1.

SEM evaluation of demineralized dentin treated with professional-strength NaF topical pastes.

Purpose: To qualitatively explore the effects of prescription-strength topical NaF pastes on patent tubules in a pH cycling model comprising remineralization and demineralization phases.

Methods: 3 mm diameter dentin cores were extracted from bovine teeth, mounted in acrylic rods, ground and polished, and initially demineralized in 10 mL unstirred 50% citric acid (pH = 1.2) for 2 minutes to remove the smear layer and expose the dentin tubules.

In situ remineralisation of eroded enamel lesions by NaF rinses.

Objective: The purpose of this pilot study was to evaluate the remineralisation of eroded enamel by NaF rinses in an intra-oral model.

Methods: Serving as their own control, subjects (N=80) participated in a randomised, four-leg (20 subjects/leg), 28-day, parallel design study. In each leg, each participant wore a customised orthodontic bracket attached to a mandibular molar that contained one tooth block having an initial erosive lesion (0.

In situ remineralization of white-spot enamel lesions by 500 and 1,100 ppm F dentifrices.

The aim of this study was to evaluate the remineralization potential of three silica-containing NaF dentifrice systems in an intraoral model. Subjects (N = 30) in this randomized, three-phase, 28-day, crossover study served as their own control. Each participant wore a customized orthodontic appliance attached to a mandibular molar and contained one tooth block with caries-like lesion.

Surfactant-modified beta-TCP: structure, properties, and in vitro remineralization of subsurface enamel lesions.

A hybrid material comprised of beta-tricalcium phosphate (beta-TCP) and sodium lauryl sulfate (SLS) was prepared using a mechanochemical process, examined using particle size analysis, IR spectroscopy, (31)P, (23)Na, and (13)C solid-state NMR spectroscopy, and calcium dissolution experiments, and probed for in vitro remineralization of subsurface enamel lesions. Our results suggest that while the (31)P environments of beta-TCP remain unchanged during solid-state processing, there is noticeable shifting among the SLS (23)Na and (13)C environments. Therefore, given the structure of beta-TCP, along with our IR examinations and calcium dissolution isotherms, SLS appears to interface strongly with the cation deficient C(3) symmetry site of the beta-TCP hexagonal crystal lattice with probable emphasis placed on the underbonded CaO(3) polyhedra.

Remineralization of eroded enamel by a NaF rinse containing a novel calcium phosphate agent in an in situ model: a pilot study.

Purpose: An in situ study evaluated the remineralization potential of 225 ppm fluoride (F) rinses with and without a calcium phosphate agent (TCP-Si-Ur) on eroded enamel.

Methods: 20 human patients participated in this IRB approved study. Enamel blocks extracted from 20 human molars were assigned to each of the three study phases (G1, G2, G3).

Preparation, characterization and in vitro efficacy of an acid-modified beta-TCP material for dental hard-tissue remineralization.

A blended material composed of beta-tricalcium phosphate (beta-TCP) and fumaric acid (FA) was prepared using a mechanochemical process. The structure and properties of the TCP-FA material was probed using particle size analysis, infrared, (31)P and (13)C solid-state nuclear magnetic resonance (NMR) spectroscopy, powder X-ray diffraction and calcium bioavailability. NMR studies showed that orthophosphate environments within beta-TCP remain largely unaffected in the presence of FA during mechanochemical processing; alternately, (13)C data indicated the carboxylic groups of FA are strongly affected during processing with beta-TCP.

In vitro remineralization efficacy of NaF systems containing unique forms of calcium.

Purpose: To determine the in vitro remineralization potential of a new calcium phosphate technology in a 1000 ppm F system.

Methods: 3 mm diameter bovine enamel specimens were mounted, ground and polished, and softened in a carbopol-lactic acid solution (pH = 5.0) for 36 hours at 37 degrees C.

In vitro assessments of experimental NaF dentifrices containing a prospective calcium phosphate technology.

Purpose: To determine the fluoride dose response of experimental NaF dentifrices containing a prospective calcium phosphate technology, along with the corresponding relative enamel and dentin abrasion values.

Methods: 3 mm diameter bovine enamel specimens were mounted, ground and polished, and softened in a carbopol-lactic acid solution (pH = 5.0) for 36 hours at 37 degrees C.