Synopsis of recent research by authors named "Allan Tsung"
- Recent research by Allan Tsung emphasizes the role of peptidyl-arginine deiminases (PADs) in promoting sepsis and acute lung injury, revealing that targeting PAD2 can reduce inflammation and bacterial burden in sepsis models while loss of both PADI2 and PADI4 improves survival in these conditions.
- Tsung's work also explores the multifaceted role of neutrophil extracellular traps (NETs) in immune defense and various diseases, underscoring their importance in both infection and sterile inflammation.
- Additionally, his research extends to the area of pancreatic cancer, examining how the protein MG53 could inhibit tumor growth, and investigating the effectiveness of current screening guidelines for high-risk pancreatic cancer patients to enhance survival outcomes.
