Anomalous Left Circumflex Artery With ST Depressions and T-wave Inversions in a Healthy Athlete: A Case Report.

An anomalous left circumflex artery is a congenital anatomic variant of typical coronary circulation that can potentially contribute to cardiac ischemia or altered blood flow. These variants can cause changes to be seen on electrocardiograms, particularly to the T wave and ST segments, including depressions, inversions, or elevations. We describe the case of a healthy 35-year-old man with previously undiagnosed anomalous origin of the left circumflex artery from the right coronary artery ostium with evidence of ST-segment changes and T-wave inversions on electrocardiogram during exercise stress testing, despite the lack of evidence of atherosclerosis and the patient being in good cardiac health otherwise.

Efficacy and Safety of Bepridil in Chronic Stable Angina Pectoris Refractory to Nifedipine.

The efficacy and safety of bepridil in chronic stable angina pectoris refractory to an extended-release preparation of nifedipine were evaluated in this open-label prospective study. Patients whose angina had not responded adequately to maximum tolerated doses of nifedipine received bepridil for 8 weeks after a 2-week baseline period at their established dose of nifedipine. Twenty-five patients entered the bepridil treatment period.