The rheological injectability of N-succinyl-chitosan solutions.

The viscosity of a set of N-succinyl-chitosan (NSC) solutions was characterized near the 0.2Pas rheological injectability limit. This is believed to be the first such report in the open literature.

Compressive stress-strain response of covalently crosslinked oxidized-alginate/N-succinyl-chitosan hydrogels.

Novel injectable hydrogels have been formed at 37°C under physiological pH using a polymer-polymer crosslinking reaction. Three different formulations were tested. After 1-day cure time at body temperature, the elastic modulus of unswollen samples ranged between 3 and 5 kPa but after 11 additional days at 4°C exceeded the target modulus of 10 kPa.