Publications by authors named "Allan Pradelli Roldao"
Article Synopsis
- Developing new painkillers is tough because many potential drugs have serious side effects due to their impact on various biological pathways beyond just pain relief.
- Researchers are focusing on targeting protein-protein interactions (PPIs) involved in pain signaling to create more effective and safer analgesics, using rodent models to evaluate their pain-reducing abilities.
- By analyzing data from sensory nerve tissues, they identified key PPIs for exploring new drug designs, suggesting that blocking specific interactions in relevant proteins may improve pain treatment while minimizing unwanted effects.
