Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease affecting motor neurons, with various atypical forms that can differ from the classic presentation, making diagnosis challenging.
A series of six patients showcased different atypical ALS presentations, where electromyography (EMG) played a critical role in confirming diagnoses, including cases of isolated bulbar ALS and Vulpian-Bernhardt syndrome.
The study underscores that ALS represents a spectrum of motor neuron diseases with no cure and a fatal prognosis, highlighting the importance of EMG in diagnosing atypical forms of the disease.