Publications by authors named "Allan L Delisle"
Article Synopsis
- M102AD is a newly designated phage that evolved from the original M102 strain of Streptococcus mutans after genome analysis revealed significant differences.
- The phage specifically infects certain serotype c strains of S. mutans and has unique characteristics regarding how it attaches to its host, demonstrating a preference for carbohydrate receptors.
- The genome consists of linear double-stranded DNA with 40 open reading frames, no lysogenic genes, and relates closely to other S. mutans phages, reinforcing the need for research using well-characterized microbial resources.
Isolation and expression of the lysis genes of Actinomyces naeslundii phage Av-1.
Appl Environ Microbiol
February 2006
Like most gram-positive oral bacteria, Actinomyces naeslundii is resistant to salivary lysozyme and to most other lytic enzymes. We are interested in studying the lysins of phages of this important oral bacterium as potential diagnostic and therapeutic agents. To identify the Actinomyces phage genes encoding these species-specific enzymes in Escherichia coli, we constructed a new cloning vector, pAD330, that can be used to enrich for and isolate phage holin genes, which are located adjacent to the lysin genes in most phage genomes.
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