"FBT Is for the Rich": A Qualitative Study Examining Clinicians' Experiences and Perceptions of Treatment Access and Engagement for Diverse Families in Family-Based Treatment.

Objective: Family-based treatment (FBT) is the leading evidence-based treatment for adolescent eating disorders, but research exploring access and engagement in FBT is sparse. This paper focuses on findings from a broader study, specifically addressing the social determinants of health (SDH) impeding access and engagement in FBT for diverse families (i.e.

Artificial intelligence (AI) for paediatric fracture detection: a multireader multicase (MRMC) study protocol.

Introduction: Paediatric fractures are common but can be easily missed on radiography leading to potentially serious implications including long-term pain, disability and missed opportunities for safeguarding in cases of inflicted injury. Artificial intelligence (AI) tools to assist fracture detection in adult patients exist, although their efficacy in children is less well known. This study aims to evaluate whether a commercially available AI tool (certified for paediatric use) improves healthcare professionals (HCPs) detection of fractures, and how this may impact patient care in a retrospective simulated study design.

Exploring the potential of flour, starch concentrate, and protein concentrate from Richlea lentils in the development of lentil based extruded puffs.

Lentil puffs were developed from a mixed design of varying weight fractions of lentil flour (x1), lentil starch concentrate (x2), and lentil protein concentrate (x3) using a twin-screw pilot scale extruder at a dry feed rate of 20 kg/h (d.b.), a water feed rate of 2 kg/h, and an extruder screw speed of 350 rpm.

Compact low-repetition-rate femtosecond optical parametric oscillators enabled by Herriott cells.

We report the design and characterization of a femtosecond optical parametric oscillator containing an intracavity Herriott cell. Pumped by a 49.16-MHz Yb:fiber laser, the signal wavelength could be tuned over 1440-1530 nm, with the Herriott cell containing 81% of the free-space cavity length required for synchronous operation.

Effects of extreme drought on the invasion dynamics of by non-native plants.

The increasing frequency of extreme droughts poses significant challenges for predicting the invasion success (or failure) of non-native plant species. While current frameworks are primarily based on moderate droughts, the unique characteristics of extreme droughts necessitate re-evaluating our understanding of plant invasion during and after extreme droughts. Here, using core principles of community assembly and invasion biology, we discuss how the invasibility of non-native plants during and after extreme droughts differs due to: (i) differences in the ecological response of the native community, (ii) barriers at different invasion stages, and (iii) the traits of non-native plants.

Service Members' Attitudes Toward Reporting Hazing Incidents.

Introduction: Addressing hazing within the U.S. Military has become a critical concern to safeguard the well-being of service members; recent attempts to assess hazing prevalence in the military have been unsuccessful due to under representative data.

"How I would like AI used for my imaging": children and young persons' perspectives.

Objectives: Artificial intelligence (AI) tools are becoming more available in modern healthcare, particularly in radiology, although less attention has been paid to applications for children and young people. In the development of these, it is critical their views are heard.

Materials And Methods: A national, online survey was publicised to UK schools, universities and charity partners encouraging any child or young adult to participate.

Critical considerations for communicating environmental DNA science.

The economic and methodological efficiencies of environmental DNA (eDNA) based survey approaches provide an unprecedented opportunity to assess and monitor aquatic environments. However, instances of inadequate communication from the scientific community about confidence levels, knowledge gaps, reliability, and appropriate parameters of eDNA-based methods have hindered their uptake in environmental monitoring programs and, in some cases, has created misperceptions or doubts in the management community. To help remedy this situation, scientists convened a session at the Second National Marine eDNA Workshop to discuss strategies for improving communications with managers.

We Don't Haze: Testing the Effectiveness of a Video-Based Hazing Prevention Training for College Students.

This research reports findings from a study to explore the efficacy of a video-based training with college students to determine the extent to which the training shifted student perceptions of hazing, increased willingness and ability to intervene in situations where hazing is occurring, and altered student perceptions of hazing social norms. The study included two experimental groups and a control group at each of the three data-gathering sessions at three U.S.

The genome sequence of the White-legged damselfly, (Pallas, 1771).

We present a genome assembly from an individual male (the White-legged damselfly; Arthropoda; Insecta; Odonata; Platycnemididae). The genome sequence is 1793.3 megabases in span.

Fast-slow traits predict competition network structure and its response to resources and enemies.

Plants interact in complex networks but how network structure depends on resources, natural enemies and species resource-use strategy remains poorly understood. Here, we quantified competition networks among 18 plants varying in fast-slow strategy, by testing how increased nutrient availability and reduced foliar pathogens affected intra- and inter-specific interactions. Our results show that nitrogen and pathogens altered several aspects of network structure, often in unexpected ways due to fast and slow growing species responding differently.

Towards mechanistic integration of the causes and consequences of biodiversity.

The global biodiversity crisis has stimulated decades of research on three themes: species coexistence, biodiversity-ecosystem functioning relationships (BEF), and biodiversity-ecosystem functional stability relationships (BEFS). However, studies on these themes are largely independent, creating barriers to an integrative understanding of the causes and consequences of biodiversity. Here we review recent progress towards mechanistic integration of coexistence, BEF, and BEFS.

The genome sequence of the Common Darter, (Charpentier, 1840).

We present a genome assembly from an individual female (the Common Darter; Arthropoda; Insecta; Odonata; Libellulidae). The genome sequence is 1349.6 megabases in span.

Modification of Commercial Polymer Coatings for Superhydrophobic Applications.

Superhydrophobic surfaces have been studied extensively over the past 25 years. However, many industries interested in the application of hydrophobic properties are yet to find a suitable solution to their needs. This paper looks at the rapid functionalization of nanoparticles and the fabrication of superhydrophobic surfaces with contact angles > 170°.

Examining clinicians' perceptions and experiences working with diverse families in family-based treatment: Common adaptations and considerations for treatment engagement.

Objective: Family-Based Treatment (FBT) is the leading manualized treatment for adolescent eating disorders; however, there is limited research on the adaptation of FBT for diverse families (i.e., families belonging to identity groups subject to systemic barriers and prejudices).

Effects of Novel Dental Composites on Biofilms.

With the phase-out of amalgam and the increase in minimally invasive dentistry, there is a growing need for high-strength composite materials that can kill residual bacteria and promote tooth remineralization. This study quantifies how antibacterial polylysine (PLS) and re-mineralizing monocalcium phosphate monohydrate (MCPM) affect biofilms and the strength of dental composites. For antibacterial studies, the MCPM-PLS filler percentages were 0-0, 8-4, 12-6, and 16-8 wt% of the composite filler phase.

Nitrogen availability and plant functional composition modify biodiversity-multifunctionality relationships.

Biodiversity typically increases multiple ecosystem functions simultaneously (multifunctionality) but variation in the strength and direction of biodiversity effects between studies suggests context dependency. To determine how different factors modulate the diversity effect on multifunctionality, we established a large grassland experiment manipulating plant species richness, resource addition, functional composition (exploitative vs. conservative species), functional diversity and enemy abundance.

Quantifying impacts of an environmental intervention using environmental DNA.

Environmental laws around the world require some version of an environmental-impact assessment surrounding construction projects and other discrete instances of human development. Information requirements for these assessments vary by jurisdiction, but nearly all require an analysis of the biological elements of ecosystems. Amplicon-sequencing-also called metabarcoding-of environmental DNA (eDNA) has made it possible to sample and amplify the genetic material of many species present in those environments, providing a tractable, powerful, and increasingly common way of doing environmental-impact analysis for development projects.

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.

KAT6A, and its paralog KAT6B, are histone lysine acetyltransferases (HAT) that acetylate histone H3K23 and exert an oncogenic role in several tumor types including breast cancer where KAT6A is frequently amplified/overexpressed. However, pharmacologic targeting of KAT6A to achieve therapeutic benefit has been a challenge. Here we describe identification of a highly potent, selective, and orally bioavailable KAT6A/KAT6B inhibitor CTx-648 (PF-9363), derived from a benzisoxazole series, which demonstrates anti-tumor activity in correlation with H3K23Ac inhibition in KAT6A over-expressing breast cancer.

Climate, host and geography shape insect and fungal communities of trees.

Non-native pests, climate change, and their interactions are likely to alter relationships between trees and tree-associated organisms with consequences for forest health. To understand and predict such changes, factors structuring tree-associated communities need to be determined. Here, we analysed the data consisting of records of insects and fungi collected from dormant twigs from 155 tree species at 51 botanical gardens or arboreta in 32 countries.

Capturing patterns of evolutionary relatedness with reflectance spectra to model and monitor biodiversity.

Biogeographic history can set initial conditions for vegetation community assemblages that determine their climate responses at broad extents that land surface models attempt to forecast. Numerous studies have indicated that evolutionarily conserved biochemical, structural, and other functional attributes of plant species are captured in visible-to-short wavelength infrared, 400 to 2,500 nm, reflectance properties of vegetation. Here, we present a remotely sensed phylogenetic clustering and an evolutionary framework to accommodate spectra, distributions, and traits.

Nitrogen translocation by Highland cattle grazing in -encroached pastures.

Unlabelled: During the last decades, has expanded over former montane pastures and meadows, due to land use and abandonment. This nitrogen-fixing woody species has triggered negative agro-environmental impacts, such as nitrogen (N) leaching, soil acidification and a reduced biodiversity. The aim of this study was to estimate the N translocation from -encroached areas to adjacent open pastures by Highland cattle.

Proof-of-concept trial of Goal Management Training to improve executive functions and treatment outcomes in methamphetamine use disorder.

Background: Deficits in executive function are common in methamphetamine use disorder (MUD), likely contributing to difficulties in sustained treatment success. Cognitive remediation interventions are designed to treat such deficits but have not been adapted to the needs of people with MUD. This study presents a proof-of-concept trial to evaluate a new cognitive remediation program for MUD, Goal Management Training (GMT).