Publications by authors named "Allan Didriksen"
Context: Vitamin D and 25-hydroxyvitamin D [25(OH)D] are stored in adipose tissue, but the clinical relevance is uncertain.
Objective: To evaluate changes in serum 25(OH)D and adipose tissue vitamin D levels after stopping vitamin D supplementation.
Design: A prospective, double-blind cohort follow-up study.
Objective: The objective was to assess the amount of vitamin D3 stored in adipose tissue after long-term supplementation with high dose vitamin D3.
Design: A cross-sectional study on 29 subjects with impaired glucose tolerance who had participated in a randomized controlled trial with vitamin D3 20 000 IU (500 μg) per week vs placebo for 3-5 years.
Methods: Abdominal subcutaneous fat tissue was obtained by needle biopsy for the measurements of vitamin D3 and 25-hydroxyvitamin D3 (25(OH)D3).
Article Synopsis
- The serum level of 25-hydroxyvitamin D (25(OH)D) is influenced not only by diet and skin production but also by genetic factors, particularly SNPs in genes related to vitamin D metabolism.
- A study analyzed data from three trials involving high doses of vitamin D supplementation to understand how genetic variations affect serum 25(OH)D levels before and after supplementation.
- It was found that individuals with specific genetic variants had lower baseline 25(OH)D levels and showed smaller increases from supplementation, while those with high body mass index (BMI) also had lower baseline levels and smaller responses after treatment.
The prevalence of gastroschisis in Norway, as reported to the Medical Birth Registry of Norway, increased regularly and sixfold from 0.5 to 2.9 per 10,000 births during 1967-1998.
View Article and Find Full Text PDF